Results 171 to 180 of about 16,480,514 (312)

Self-care in children and young people with complex chronic conditions instrument: development and content validation. [PDF]

Int J Nurs Stud Adv
Manzi G, Biagioli V, Mascolo R, Gawronski O, Kania V, Selvaggio D, Ferro D, Grimaldi Capitello T, Salata M, Ricci R, Rocco G, Vellone E, Tiozzo E, Raponi M, Dall'Oglio I, Self-care CYP Study Group.   +15 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Cross-cultural assessment of knowledge and attitudes toward Folic acid: Instrument development and validation in Thailand and Yemen. [PDF]

PLoS One
Al-Qaari RA, Khuankaew S, Suttiserm M, Pornsuksawang S, Boonnop P, Manopatanakul S, Khovidhunkit SP, Thiradilok S, Tantipoj C.   +8 more
europepmc   +1 more source

Non-Destructive Determination of Bayberry Sugar and Acidity by Hyperspectral Remote Sensing of Si-Sensor and Low-Cost Portable Instrument Development. [PDF]

Sensors (Basel), 2023
Wang J, Wu W, Tian S, He Y, Huang Y, Wang F, Zhang Y.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Potential for Algorithmic Bias in Clinical Decision Instrument Development. [PDF]

NPJ Digit Med
Obra JK, Singh C, Watkins K, Feng J, Obermeyer Z, Kornblith A.   +5 more
europepmc   +1 more source

Environmental Risk Assessment of Low Back Pain in ICU Nurses: An Instrument Development Study. [PDF]

J Nurs Manag, 2023
Zhang L, Liu Y, Yuan S.
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Assessing the national essential medicines list selection processes: Instrument development and testing. [PDF]

PLoS One
Saxena E, Kohler JC, Thorpe KE, Persaud N.   +3 more
europepmc   +1 more source

An Integrated Model for Evaluating the Sustainability of Gamified Mobile Health Apps: An Instrument Development and Validation. [PDF]

Healthcare (Basel), 2023
Mustafa AS, Ali N, Dhillon JS, Sedera D.
europepmc   +1 more source