Results 171 to 180 of about 3,230,793 (311)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

An instrument to measure the solar spectrum from 170 to 3200 nm on board Spacelab [PDF]

This instrument, at the present time in development, will fly on board Spacelab I in May 1983. Other flights are foreseen during the following missions. The instrument is composed of three double monochromators covering the range 170 to 3200 nm.
Labs, D., Meckel, H., Pastiels, R., Simon, P. C., Thuiller, G.   +4 more
core   +1 more source

Systematic Nutritional Clinical Assessment (SyNCA): Instrument Development, Delphi Protocol for Content, and Semantic Validation. [PDF]

J Hum Nutr Diet
Jesus RP, Oliveira LPM, Cunha CM, Boulhosa RSDSB, Porto Ricci ACB, Arruda MR, Batista ACV, Santos KMS, Pereira KG, Romeiro FG, de Castro Lyra A, Bueno AA.   +11 more
europepmc   +1 more source

Childbirth Readiness Scale (CRS): instrument development and psychometric properties. [PDF]

BMC Pregnancy Childbirth, 2022
Mengmei Y, Meizhen Z, Tieying Z, Meiliyang W, Ye C, Ke Z, AiQing T.   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A multidimensional procurement literacy instrument: Development and validation among undergraduate procurement students in Ghana. [PDF]

PLoS One
Oppong PB, Ofori D, Wunu P, Nyamah EY, Nyamah EY, Boateng JKGA, Agyapong GKQ.   +6 more
europepmc   +1 more source

Building the Business Case for an Inclusive Approach to Digital Health Measurement With a Web App (Market Opportunity Calculator): Instrument Development Study. [PDF]

JMIR Form Res, 2023
Tang M, Sharma Y, Goldsack JC, Stern AD.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Develop real-time dosimetry concepts and instrumentation for long term missions [PDF]

The development of a rugged portable instrument to evaluate dose and dose equivalent is described. A tissue-equivalent proportional counter simulating a 2 micrometer spherical tissue volume was operated satisfactorily for over a year.
Braby, L. A.
core   +2 more sources

Digital maturity index instrument development for primary health care in Indonesia: a sequential exploratory mixed-methods approach. [PDF]

BMC Health Serv Res
Anwar SJ, Sunjaya DK, Hilfi L, Rinawan FR, Ardisasmita MN, Diah Herawati DM.   +5 more
europepmc   +1 more source