Results 61 to 70 of about 776,442 (262)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Development and validation of cohabitation intentions scale (CIS)

Cogent Psychology
The relationship between attitudes and behaviour is largely defined by intentions. The stronger the intention to engage in a behaviour, the greater the likelihood that attitudes will predict that behaviour.
Angela A. Gyasi-Gyamerah, Christabel Quansah, Christopher M. Amissah, Kwasi Gyasi-Gyamerah   +3 more
doaj   +1 more source

INSTRUMENT DEVELOPMENT OF HIGHER ORDER THINKING SKILL IN MATHEMATICS INSTRUCTIONAL ON SENIOR HIGH SCHOOL

JISAE (Journal of Indonesian Student Assessment and Evaluation), 2015
The purpose of this research was to develop an instrument that can be used to measure higher-order thinking skills (HOTS) in mathematics instructional of high school students.
Benidiktus Tanujaya
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Two new positive psychosocial measures for persons living with dementia

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Differences in adaptive strategies used by individuals and families living with dementia have the potential to impact day‐to‐day well‐being.
Sheila L. Molony, Sam Fazio, Kimberly Van Haitsma, Richard Feinn, Joseph Montminy, Maureen Rulison, Ricci Sanchez, Sheryl Zimmerman   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The development and preliminary validation of a social-emotional skills assessment instrument for lower secondary school students [PDF]

Psihološka Istraživanja
Given the necessity of existence of comprehensive and psychometrically sound instruments that measure students' social-emotional skills (SEMS) in school context and facet-level, this study aims to develop and evaluate a SEMS assessment instrument for ...
Einpaul Piret, Leijen Äli, Baucal Aleksandar   +2 more
doaj   +1 more source

Policies and instruments for social development

Journal of Innovations and Sustainability, 2018
Current paper presents a book review made by Prof. Dr. Margarita Bogdanova on the monograph “Policies and instruments for social development” – an edition of Innovations and Sustainability Academy – Bulgaria authored by Corresponding Member of the Russian Academy of Natural History Prof. Dr. Eng. Venelin Terziev.
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source