Results 171 to 180 of about 2,410,614 (280)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Quantification of Intact MDa Poly(A)-Tailed and Non-Tailed mRNA Fractions with Charge Detection Mass Spectrometry. [PDF]

Anal Chem
Robles J, Miller ZM, Roe AM, Thibert SM, Gardner MR, Magaling JTM, Torpey JW, Castañeda AF, Williams ER.   +8 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Farm-Level Biosecurity and Antimicrobial Use in Pig Production: An Integrated Inferential and Explainable Machine Learning Analysis. [PDF]

Vet Sci
Vribék K, Farkas M, Csorba S, Süth M, Gombos L, Kerek Á, Imre E, Somogyi Z, Jerzsele Á, Farkas Z.   +9 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Evaluation of bending test, cyclic fatigue, and buckling resistance test using rotary Nickel-Titanium files of three types: An <i>in vitro</i> study. [PDF]

J Conserv Dent Endod
Jiffri S, Abumostafa A.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

A two-stage deep learning framework for lead instrument recognition in polyphonic music featuring Chinese instruments. [PDF]

PLoS One
Zheng J, Cao M, Zhang C.
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

When Cronbach's Alpha Is Not Enough: Implications for the Clinical Use of Vision-Related Patient-Reported Outcomes. [PDF]

Vision (Basel)
Cantó-Cerdán M, Martínez-Hergueta MC, Siverio-Colomina A, Yébana-Rubio P, Alió-Del-Barrio J, Cacho-Martínez P, García-Muñoz Á, Martínez-Abad A.   +7 more
europepmc   +1 more source