Results 291 to 300 of about 418,975 (381)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Iridium Oxide Inverse Opal Anodes with Tailored Porosity for Efficient PEM Electrolysis

Advanced Functional Materials, EarlyView.
The synthesis of Iridium‐based Inverse Opals (Ir‐IO) is reported as electrocatalyst for Proton exchange membrane water electrolysis (PEM‐WE). Using the developed protocol it produces highly porous materials consisting either of metallic, oxidic Iridium or a combination thereof with large surface areas.
Sebastian Möhle, Matthias Kroschel, Peter Strasser   +2 more
wiley   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

Correlation between Instrumental Activities of Daily Living and Muscle Mass in Older Adults: Impact of Comorbidities. [PDF]

Ann Geriatr Med Res
Fernández-Millones ML, Curi-Vilchez GS, Parodi JF, Runzer-Colmenares FM.   +3 more
europepmc   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

Advanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari, Sanchyan Bhowmik, Kaiwen Zhang, Chayla L. Reeves, Danielle Vahala, Yu Suk Choi, Amy Gelmi, Alexander N. Combes, Rocky S. Tuan, Vinh X. Truong, John S. Forsythe, Jessica E. Frith   +11 more
wiley   +1 more source

Predictors of basic and instrumental activities of daily living among older adults with multiple chronic conditions. [PDF]

BMC Geriatr
Jafari-Koulaee A, Mohammadi E, Fox MT, Rasekhi A, Akha O.   +4 more
europepmc   +1 more source

Diagnostic accuracy of Instrumental Activities of Daily Living for dementia in community-dwelling older adults

Age and Ageing, 2018
Hui-Fen Mao, Ling‐Hui Chang, A. Tsai, W. Huang, Li-Yu Tang, Huey-Jane Lee, Yu Sun, Ta-Fu Chen, Ker‐Neng Lin, Pei-Ning Wang, Y. Shyu, M. Chiu   +11 more
semanticscholar   +1 more source

Predicting Aggregation Behavior of Nanoparticles in Liquid Crystals via Automated Data‐Driven Workflows

Advanced Functional Materials, EarlyView.
Herein, a comprehensive framework that enabled the optimization of colloidal solubility within a high‐dimensional parameter space and study of reversible assembly processes is developed. This data‐driven workflow integrated innovations including the robotic platform for automated AuNPs functionalization, machine learning for predicting and revealing ...
Yueyang Gao, Niamh Mac Fhionnlaoich, Max Besenhard, Arun Pankajakshan, Federico Galvanin, Stefan Guldin   +5 more
wiley   +1 more source

Using Objective and Subjective Measures of Cognition to Predict Instrumental Activities of Daily Living Abilities in Multiple Sclerosis. [PDF]

Int J MS Care
Rubel A, DelMastro HM, Ruiz JA, Lo AC, Gromisch ES.   +4 more
europepmc   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source