Results 111 to 120 of about 506,439 (327)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Ownership, Control and Corporate Performance after Large-Scale Privatization [PDF]

open access: yes
We analyze the effects of ownership type and concentration on performance of a population of firms in a model large-scale privatization economy. Using specifications based on first-differences and unique instrumental variables, we find that few types of ...
Evzen Kocenda, Jan Hanousek, Jan Svejnar
core   +3 more sources

Anchored in Place: How Funders Are Helping Anchor Institutions Strengthen Local Economies [PDF]

open access: yes, 2017
This report issued by the Funders' Network as part of their Anchors Institution Funders' Group, examines the potential these deeply rooted local enterprises hold to create lasting and sustainable change—and illustrates how funders are working with anchor
Katherine Pease
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Introducing STEM Majors to the Teaching Profession Through Authentic Experiences as Tutors

open access: yesCurrent Issues in Education, 2010
Recruiting people with rich backgrounds in science, technology, engineering, and mathematics (STEM) into the teaching profession has historically been difficult and remains so today. In this bounded instrumental case study, undergraduate STEM majors were
Grinell Smith
doaj  

Engaging Impasse: Nurturing a Culture of Dialogic Engagement on a University Campus

open access: yesJournal of Communication Pedagogy
Universities have historically fostered spaces where students, faculty, staff, and administration can fruitfully engage in discussion around contentious issues.
Patricia Ann Hawk
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The role of higher education in social and cultural transformation [PDF]

open access: yes, 2010
This paper forms one of the contributions to CHERI's research report 'Higher education and society'.
Cochrane, Allan, Williams, Ruth
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

How Much Help Is Exchanged in Families? Towards an Understanding of Discrepant Research Findings [PDF]

open access: yes
Responding to claims that contemporary families had abandoned their elderly members, gerontologists over the past 30 years have provided extensive documentation of intergenerational familial support.
Carolyn J. Rosenthal, Leroy O. Stone
core  

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