Results 131 to 140 of about 506,439 (327)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN FAMILY SUPPORT AND DIET PROVISION IN DIABETES PATIENTS

open access: yesNurse and Holistic Care
Introduction: Effective diabetes management requires strict adherence to dietary guidelines. Family support plays a critical role in helping patients with diabetes maintain appropriate nutritional practices.
Velenia Kahi Timba   +3 more
doaj   +1 more source

Other instruments to help diagnose obstructive sleep apnea syndrome

open access: yesArquivos de Gastroenterologia, 2023
Rosales Picón Silvana ANGELA   +1 more
openaire   +4 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

International coalitions in Brazil’s foreign policy: security and governance reform

open access: yesRevista CIDOB d'Afers Internacionals, 2012
The text analyses the relevance and role of international coalitions as instruments and arenas for negotiation in the context of Brazilian foreign policy under Luis Inácio Lula da Silva (2003-2010), and the perspectives they bring to the attainment of ...
Alcides Costa Vaz
doaj  

Interactive homework to support student learning of measurement uncertainty in quantum mechanics

open access: yesPhysical Review Physics Education Research
[This paper is part of the Focused Collection in Investigating and Improving Quantum Education through Research.] When thinking about measurement uncertainty in a laboratory experiment that features quantum mechanical effects, it is important to consider
Gina Passante, Antje Kohnle
doaj   +1 more source

Native Americans Explore Heritage [PDF]

open access: yes, 2014
Five Native American students, all with ties to Montana, are working to share their culture through the Native American Student ...
Linfield Magazine Staff, Mileham, Mardi
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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