Results 101 to 110 of about 1,370,556 (306)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Recent experimental evidence suggests that some people dislike telling lies, and tell the truth even at a cost. We use experiments as well to study the socio-demographic covariates of such lie aversion, and find gender and religiosity to be without ...
López Pérez, Raúl, Spiegelman, Eli
core
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Diagnostic Instruments for Value Congruence
<p><em>A comparative analysis of the studies of congruence of personal and organizational values is presented in the article. Forty publications of 1999-2012 reviewed in Emerald, Sage, APA PsycNET, Wiley, ScienceDirect, Routledge, Springer and other databases have been selected for the comparative analysis.
Jolita Vveinhardt, Evelina Gulbovaite
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Alexithymia and the Reduced Ability to Represent the Value of Aversively Motivated Actions
Alexithymia is a subclinical trait defined by difficulties in identifying and describing feelings and a cognitive style avoidant of introspection. Extensive literature shows that alexithymia is characterized by multifaceted impairments in processing ...
Francesca Starita +1 more
doaj +1 more source
Valid Confidence Intervals and Inference in the Presence of Weak Instruments [PDF]
We investigate confidence intervals and inference for the instrumental variables model with weak instruments. Wald-based confidence intervals perform poorly in that the probability they reject the null is far greater than their nominal size. In the worst
Charles R. Nelson +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Essential variables are a well-established tool to support the calculation of ecological indicators. The recently conceptualized Essential Ecosystem Service Variables (EESVs) are regrouped into six classes – Ecological Supply, Demand, Use, Relational ...
Sebastian Theis +4 more
doaj +1 more source
Institutional causes of macroeconomic volatility [PDF]
In this paper we investigate the relation between the quality of institutions and macroeconomic volatility. Using instrumental variable regressions, we show that higher barriers to entry lead to higher volatility.
Levon Barseghyan, Riccardo DiCecio
core

