Results 61 to 70 of about 236,594 (266)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Dynamics of Terminal and Instrumental Values of Education on the Example of MGIMO Students

open access: yesVestnik MGIMO-Universiteta, 2015
Attitude towards derivable knowledge as a process of satisfaction of cognition needs and also as opportunity for developing flairs and making self-improvement can be called terminal.
Alexander L. Temnitskiy
doaj   +4 more sources

Scientific Publications by Russian University Students: Resource Factors and Their Effects

open access: yesВысшее образование в России
The article examines the problem of identifying student scientific publications in terms of their resource potential and the experience of forming personal cases of students in Russian universities.
E. A. Popov
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Values of young people in Tyumen region

open access: yesИзвестия высших учебных заведений: Социология. Экономика. Политика
This study is dedicated to the values of young people living in Tyumen region. The purpose of the study is to examine the value of the studying and working youth in Tyumen region.
L. N. Shabatura   +2 more
doaj   +1 more source

Value priorities and their relations with quality of life in the Baby Boomer generation of Lithuanian nurses: a cross-sectional survey

open access: yesBMC Nursing, 2007
Background The understanding of the values of nurses is especially important, since nurses constitute 80% of workforce in the healthcare system in Lithuania. In addition to that, nursing is one of the major constituents of healthcare.
Jakusovaite Irayda   +1 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Instrumental Values as Predictors of Religious Experience in the Lives of Students of Pedagogy and of Philosophy

open access: yesReligions, 2015
This article seeks to demonstrate the existence of a relationship between instrumental values and religious experience—in this instance, the experiences of God’s presence and of God’s absence in the lives of Polish students of pedagogy and of philosophy.
Stanisław Głaz
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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