Results 91 to 100 of about 1,034,990 (293)

Proposal of methodology and test protocol for evaluating and qualifying pH measuring devices

open access: yesBrazilian Archives of Biology and Technology, 2006
We present a proposal for evaluating and qualifying pH measuring devices based on the requirements of relevant standards. The proposal presented is based on ASTM E70, NBR 7353, JIS Z 8805, BS 3145, DIN 19268, NBR ISO 17025 and other standards, as well as
Niza Helena de Almeida, Percy Nohama
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Desenvolvimento de um dispositivo eletrônico para calibração de sensores de umidade do solo Development of eletronic device to calibrate soil moisture sensors

open access: yesEngenharia Agrícola, 2007
Com o advento da eletrônica e a disponibilidade de "software" de processamento, vários tipos de transdutores têm sido testados, visando à determinação da umidade do solo.
Raimundo A. de O. Leão   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Caracterização morfomecânica para beneficiamento do fruto da castanha-de-cutia (Couepia edulis) Cutia-chesnut (Couepia edulis) morphomechanical characterization for fruit processing

open access: yesRevista Brasileira de Fruticultura, 2004
A castanha-de-cutia (Couepia edulis (Prance) Prance) é um fruto fibroso encontrado na Amazônia Ocidental contendo uma amêndoa muito saborosa que os caboclos daquela região costumam consumir torrada e moída com a farinha de mandioca.
José Dalton Cruz Pessoa   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Estadística Piloto: paquete estadístico digital educacional para las investigaciones epidemiológicas Piloto's statistics: a digital-educational statistical package for the epidemiological researches

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2010
Introducción: El uso práctico de la Bioestadística es una preocupación de cualquier investigador. Objetivo: Con el objetivo de facilitar el cálculo matemático de las pruebas estadísticas utilizadas en las investigaciones epidemiológicas, su aplicación e ...
Manuel Piloto Morejón
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Review of measurement and testing problems [PDF]

open access: yes, 1976
Good instrumentation was required to obtain reliable and repeatable baseline data. Problems that were encountered in developing such a total system were: (1) accurate airflow measurement, (2) precise fuel flow measurement, and (3) the instrumentation ...

core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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