Results 61 to 70 of about 1,034,990 (293)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sensor & instrumentation system : series 2 [PDF]
, 2017 This book is an introduction to a number of the topics in sensor and instrumentation systems. Many of the topics describe the design experiments and system measurement especially in sensor applications.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Review of biological mechanisms for application to instrument design [PDF]
, 1967 Biological sensors are the mechanisms which enable a living organism to monitor its environment. Ways in which the functional mechanism of biosensors can be applied to develop new concepts of instrumentation, enhance and extend the human senses, and ...
Healer, J.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Further Development of the Tromsø CCD Photometer
Open Astronomy, 2003 A brief summary of the improvements recently made by the Vilnius WET group to Tromsø CCD photometer for time resolved photometry is provided.
Janulis R.
doaj +1 more source
Graphene-Based Materials for Biosensors: A Review
Sensors, 2017 The advantages conferred by the physical, optical and electrochemical properties of graphene-based nanomaterials have contributed to the current variety of ultrasensitive and selective biosensor devices.
Phitsini Suvarnaphaet +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Sensors, 2018 In this paper, we report a theoretical framework on the effect of multiple resonances inside the dielectric cavity of insulator-insulator-metal-insulator (IIMI)-based surface plasmon sensors.
Phitsini Suvarnaphaet +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source