Results 41 to 50 of about 21,443 (217)

Energy resolving CT systems using Medipix2 and MHSP detectors

, 2022
Art. C03022, 12 S.Energy resolved imaging has been possible with a newest generation of radiation detectors with photon counting and spectroscopic capabilities.
Veloso, J.F.C.A., Firsching, M., Silva, A.L.M., Nachtrab, F., Uhlmann, N., Carramate, L.F.N.D., Silva, A.M. da   +6 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Beamline instrumentation in the 2004 combined ATLAS testbeam

, 2005
This note describes the beamline instrumentation, such as scintillators, beamchambers and Cherenkov detectors, and extra detectors, used in the 2004 combined testbeam of the ATLAS detector. The readout of these detectors via two VME crates, and the setup
Di Girolamo, B, Volpi, M, Pribyl, L, Dotti, A, Giangiobbe, V, Johansson, P   +5 more
core  

The BLAST Cherenkov detectors

, 2005
We report on the design, construction, and operation of a large array of diffusely reflective aerogel Cherenkov detectors. They are part of the detector instrumentation of the Bates Large Acceptance Spectrometer Toroid (BLAST) at the MIT-Bates Linear ...
Alarcon, R., Degrush, A., Tonguc, B., Calarco, John R., Prince, J., Filoti, O., Geis, E., Kelsey, J., Botto, T., Six, E., Vidal, C.   +10 more
core   +1 more source

Printing out Particle Detectors with 3D-Printers - a Potentially Transformational Advance for HEP Instrumentation [PDF]

, 2020
-This white paper suggests posing a "grand challenge" to the HEP instrumentation community, i.e. the aggressive development of additive manufacturing, also known as 3D-printing, for the production of particle detectors in collaboration with ...
M Hohlmann
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Design and experimental investigation of a planar metamaterial Silicon based lenslet [PDF]

, 2020
The next generations of ground-based cosmic microwave background experiments will require polarisation sensitive, multichroic pixels of large focal planes comprising several thousand detectors operating at the photon noise limit.
James Beall, Jaehnig, Gregory, Austermann, Jason, Aritoki Suzuki, Raymind, Benjamin, Gregory Jaehnig, Nils Halverson, Benjamin Raymond, Pisano, Giampaolo, Gascard, Thomas, Shitvov, Alexey, Johannes Hubmayr, Doyle, Simon, Hubmayr, Johannes, Thomas Gascard, McKenney, Christopher, Beall, James, Jason Austermann, Halverson, Nils, Simon Doyle, Alexey Shitvov, Christopher M. McKenney, Giampaolo Pisano, Suzuki, Aritoki   +23 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

14th ICATPP Conference on Astroparticle, Particle, Space Physics and Detectors for Physics Applications

, 2014
The exploration of the subnuclear world is done through increasingly complex experiments covering a wide range of energy and performed in a large variety of environments ranging from particle accelerators, underground detectors to satellites and the ...
Price, Lawrence, Rancoita, Pier-Giorgio, Leroy, Claude, Ruchti, Randy, Giani, Simone   +4 more
core   +1 more source

Practical considerations in developing nuclear detectors for tokamak harsh environments

, 2022
Fusion tokamaks (FT) and hybrid fusion-fission reactors (HFFR) present harsh working conditions characterized by intense neutron and gamma fluxes (>1012 cm-2 s-1), high working temperatures (up to 600 °C) and corrosive environment.
Raj, P., Angelone, M.
core   +1 more source