Results 21 to 30 of about 4,908 (228)

Developing A Minor Program In Computer Based Measurement And Instrumentation For Undergraduate Science And Engineering Majors [PDF]

open access: yes2002 Annual Conference Proceedings, 2020
Comment: 9 ...
Sanjeev Arora   +2 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

COMPUTATIONAL THINKING INSTRUMENTS AS A PROBLEM-SOLVING METHOD IN OBJECT-ORIENTED PROGRAMMING MATERIALS IN VOCATIONAL SCHOOLS

open access: yesJurnal Teknologi Informasi Universitas Lambung Mangkurat (JTIULM), 2023
This study aims to develop a Computational Thinking (CT) instrument on Object-Oriented Programming material as a tool for measuring the level of CT in the problem-solving abilities of Vocational High School students. The Plomp model of R&D analysis is used as a research flow. There are four stages of CT instrument development, namely 1) preliminary
null Eka Fitrajaya Rahman   +2 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Assessing computer program reading comprehension skill in pre-service teachers: The development and piloting of a screening instrument in Scratch

open access: yesAtti del 5° Convegno sulle didattiche disciplinari, 2022
The recent addition of computer science and computer programming to primary school curricula worldwide introduces the challenge of bringing primary school teachers up to speed in this new learning domain. Assessments are needed to determine their knowledge and competencies in this area.
Eva Marinus   +2 more
openaire   +1 more source

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