Results 61 to 70 of about 1,330,014 (301)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Visual Program Distillation: Distilling Tools and Programmatic Reasoning into Vision-Language Models [PDF]

open access: yesarXiv, 2023
Solving complex visual tasks such as "Who invented the musical instrument on the right?" involves a composition of skills: understanding space, recognizing instruments, and also retrieving prior knowledge. Recent work shows promise by decomposing such tasks using a large language model (LLM) into an executable program that invokes specialized vision ...
arxiv  

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Adding traceability to an educational IDE : a thesis presented in partial fulfilment of the requirements for the Master degree in Computer Science at Massey University, Manawatu, New Zealand [PDF]

open access: yes, 2016
High dropout and failure rate in introductory programming courses indicate the need to improve programming comprehension of novice learners. Some of educational tools have successfully used game environments to motivate students. Our approach is based
Sui, Li
core  

Extensible Technology-Agnostic Runtime Verification

open access: yes, 2013
With numerous specialised technologies available to industry, it has become increasingly frequent for computer systems to be composed of heterogeneous components built over, and using, different technologies and languages.
Colombo, Christian   +3 more
core   +2 more sources

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

open access: yesFEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti   +5 more
wiley   +1 more source

PyCOOL - a Cosmological Object-Oriented Lattice code written in Python [PDF]

open access: yes, 2012
There are a number of different phenomena in the early universe that have to be studied numerically with lattice simulations. This paper presents a graphics processing unit (GPU) accelerated Python program called PyCOOL that solves the evolution of scalar fields in a lattice with very precise symplectic integrators.
arxiv   +1 more source

CONFLLVM: A Compiler for Enforcing Data Confidentiality in Low-Level Code

open access: yes, 2019
We present an instrumenting compiler for enforcing data confidentiality in low-level applications (e.g. those written in C) in the presence of an active adversary.
Bhatu, P.   +8 more
core   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

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