Results 71 to 80 of about 1,290,646 (262)

To the question of skull trepa nation. Historical excursion

open access: yesВестник хирургии имени И.И. Грекова
The article presents information highlighting some moments of the evolution of surgical instruments used to perform skull trepanation from ancient times up to the Modern Age (late 19th century), when the period of skull surgery ended and a new surgical ...
A. Yu. Ulitin   +4 more
doaj   +1 more source

Research Instrument: Instrument Development and Instrument Calibration

open access: yesAl Hikmah Indonesian Journal of Early Childhood Islamic Education
The development and calibration of research instruments are crucial components in ensuring the accuracy and reliability of data collection in educational and social sciences. This study addresses the issues surrounding the creation and refinement of research instruments, emphasizing the importance of instrument validity and reliability.
Rizal Firdaus   +2 more
openaire   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Proceso de adaptación al castellano del Charing Cross Venous Ulcer Questionnaire (CCVUQ) para medir la calidad de vida relacionada con la salud en pacientes con úlceras venosas Spanish adaptation process of the Charing Cross Venous Ulcer Questionnaire (CCVUQ) to measure the quality of life related to health in patients with venous ulcers

open access: yesGerokomos, 2010
Introducción: la medición de la calidad de vida relacionada con la salud (CVRS) permite, en gran medida, contribuir a mejorar la calidad del cuidado. Se ha constatado que la CVRS de las personas con úlceras venosas (UV) está afectada negativamente.
Renata Virginia González-Consuegra   +1 more
doaj  

DEVELOPMENT OF SUSTAINABLE TOURISM INSTRUMENTS FOR ECOLOGICAL RESILIENCE IN PARI ISLAND, DKI JAKARTA

open access: yesGeoEco
The research objective is to develop an instrument for assessing sustainable tourism in the context of ecological resilience in Pari Island, DKI Jakarta. This study uses research and development methods through the ADDIE model approach.
Samadi Samadi, Aris Munandar
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Linking ramped pyrolysis isotope data to oil content through PAH analysis

open access: yesEnvironmental Research Letters, 2013
Ramped pyrolysis isotope ( ^13 C and ^14 C) analysis coupled with polycyclic aromatic hydrocarbon (PAH) analysis demonstrates the utility of ramped pyrolysis in screening for oil content in sediments.
Matthew A Pendergraft   +5 more
doaj   +1 more source

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