Results 121 to 130 of about 167,557 (304)
Frontiers in Neuroscience, 2016 Addiction to alcohol remains a major social and economic problem, in part because of the high motivation for alcohol that humans exhibit and the hazardous binge intake this promotes.
Kelly Lei +5 more
doaj +1 more source
Altered intrinsic functional coupling between core neurocognitive networks in Parkinson\u27s disease [PDF]
, 2015 Parkinson3s disease (PD) is largely attributed to disruptions in the nigrostriatal dopamine system. These neurodegenerative changes may also have a more global effect on intrinsic brain organization at the cortical level.
Cronin-Golomb, Alice +4 more
core +1 more source
iNew Medicine, EarlyView.In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu +10 more
wiley +1 more source
, 2012 Projects for Transformation. The second part of this study presents a selection of projects developed by the five research units for the analyzed case studies. Since the objectives of the transformation processes are at least partly clear from the very beginning of the analytical work, the orientation of the designs actually also determines the type of
openaire +1 more source
iNew Medicine, EarlyView.ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang +8 more
wiley +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca +3 more
wiley +1 more source
Can trigeminal sensations impact saltiness perception? A mini‐review
Journal of the Science of Food and Agriculture, EarlyView.Abstract Many food companies have begun to reduce the salt content in their products due to health concerns; however, this reduction in salt content can affect the food's sensory appeal and flavour complexity. Flavour is defined as a combination of odour (i.e., smell), taste (i.e., gustation) and trigeminal sensations (i.e., chemesthesis).
Emily Dolan +2 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra +5 more
wiley +1 more source
Movement Disorders, EarlyView.(1) To sample subjective patient rating using the Visual Analogue Scale (VAS), random stimulation parameters were presented to the study subjects. (2) Next, corresponding volumes of tissue activated (VTA) were generated and paired with VAS values.
Sophia Peschke +9 more
wiley +1 more source
Aberrant Beta‐Band Network Alteration Preceding Freezing of Gait in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Background Freezing of gait (FOG) is a debilitating motor symptom observed in the advanced stages of Parkinson's disease (PD), characterized by an abrupt inability to initiate or continue forward walking. Whole‐brain functional connectivity analysis has shown promise in elucidating the underlying pathophysiology and identifying potential ...
Yanqiu Tian +3 more
wiley +1 more source