Results 221 to 230 of about 826,191 (386)

HUMAN GRANULOSA CELLS SYNTHESIZE LOW MOLECULAR WEIGHT INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN [PDF]

, 1989
Anne‐Maria Suikkari, Jyrki Jalkanen, Riitta Koistinen, Ralf Bützow, Olli Ritvos, TAPIO RANTA, Markku Seppälä   +6 more
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Roles of Insulin-Like Growth Factor-1 in Muscle Wasting and Osteopenia in Mice with Hyponatremia. [PDF]

Calcif Tissue Int
Kawao N, Nishikawa A, Matsumura D, Yamada A, Ohira T, Mizukami Y, Kaji H.   +6 more
europepmc   +1 more source

Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors.

, 1989
William H. Daughaday, Milan Kapadia
openalex   +1 more source

Focal expression of insulin-like growth factor I in rat kidney collecting duct. [PDF]

, 1988
J. D. Bortz, Peter Rotwein, D. L. DeVol, Peter J. Bechtel, V. A. Hansen, Marc R. Hammerman   +5 more
openalex   +1 more source

DeepCCDS: Interpretable Deep Learning Framework for Predicting Cancer Cell Drug Sensitivity through Characterizing Cancer Driver Signals

Advanced Science, EarlyView.
DeepCCDS leverages prior knowledge and self‐supervised learning to model cancer driver signals for drug sensitivity prediction. It captures complex regulatory patterns enabling more biologically informed representations. The framework outperforms existing methods across datasets, offering improved accuracy and interpretability.
Jiashuo Wu, Jiyin Lai, Xilong Zhao, Ziyi Wang, Yongbao Zhang, Liqiang Wang, Yinchun Su, Yalan He, Siyuan Li, Ying Jiang, Junwei Han   +10 more
wiley   +1 more source

Association of insulin-like growth factor 1 and metabolic parameters with mild subclinical hypothyroidism in obese boys. [PDF]

Sci Rep
Xue J, Li C, Ju J, Liang S.
europepmc   +1 more source

Insulin and Insulin-Like Growth Factor I Both Stimulate Metabolism, Growth, and Differentiation in the Postneurula Chick Embryo* [PDF]

, 1987
M. Marqués Girbau, Juan A. Gomez, Maxine A. Lesniak, Flora de Pablo   +3 more
openalex   +1 more source

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

Advanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi, Pan Duan, Mengmeng Zhu, Rong Zhang, Zihua Zhao, Xin Nie, Hanhou He, Li Hou, Xianhui Wang   +8 more
wiley   +1 more source

The signaling landscape of insulin-like growth factor 1. [PDF]

J Biol Chem
Khan MZ, Zugaza JL, Torres Aleman I.
europepmc   +1 more source