Results 231 to 240 of about 498,256 (338)

Discriminatory performance of insulin-like growth factor 1 and insulin-like growth factor binding protein-3 by correlating values to chronological age, bone age, and pubertal status for diagnosis of isolated growth hormone deficiency. [PDF]

Ann Pediatr Endocrinol Metab, 2020
Choi YJ, Lee YJ, Lee NY, Lee SH, Kim SK, Ahn MB, Kim SH, Cho WK, Cho KS, Jung MH, Suh BK.   +10 more
europepmc   +1 more source

Recombinant human insulin-like growth factor binding protein 3 inhibits growth of human epidermal growth factor receptor-2-overexpressing breast tumors and potentiates herceptin activity in vivo.

Cancer Research, 2006
Lori Jerome, N. Alami, S. Bélanger, Viviane Pagé, Q. Yu, J. Paterson, L. Shiry, M. Pegram, B. Leyland-Jones   +8 more
semanticscholar   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Insulin-like growth factor-binding protein-3 inhibition of prostate cancer growth involves suppression of angiogenesis

Oncogene, 2007
Bin Liu, Kuk-Wha Lee, M. Anzo, B. Zhang, X. Zi, Y. Tao, L. Shiry, M. Pollak, Shuo Lin, Pinchas Cohen   +9 more
semanticscholar   +1 more source

A Bioinstructive Injectable Hydrogel for Enhancing Intrinsic Regeneration through Cell Recruitment and Training

Advanced Science, EarlyView.
A bioinstructive injectable hydrogel enables sustained release of stromal cell–derived factor‐1 alpha (SDF‐1α) and stable retention of laminin through ionic and hydrophobic interactions. This dual‐signaling matrix promotes endogenous stem cell recruitment and training, supports angiogenesis, and enhances intrinsic regenerative processes in ischemic ...
Yurim Kim, Young‐Min Kim
wiley   +1 more source

Effects of insulin-like growth factor binding protein 3 on cell growth and tumorigenesis in oral squamous cell carcinoma. [PDF]

Transl Cancer Res, 2019
Xu HY, Zhu DW, Zhong LP, Zhang ZY, Yang CZ, Yang X, Zhang P.   +6 more
europepmc   +1 more source

Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor-Binding Protein 3 in Relation to the Risk of Type 2 Diabetes Mellitus: Results From the EPIC-Potsdam Study.

American Journal of Epidemiology, 2016
D. Drogan, M. Schulze, H. Boeing, T. Pischon   +3 more
semanticscholar   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source