Results 301 to 310 of about 498,256 (338)

Insulin-like growth factor–binding protein-3 and breast cancer survival

International Journal of Cancer, 1998
Insulin-like growth factors (IGFs) are potent mitogens involved in the regulation of cell proliferation and apoptosis. The action of IGFs is mediated through a specific cell membrane receptor (IGF-IR), and the interactions between IGFs and this receptor are regulated by IGF-binding proteins (IGFBPs).
H, Yu, M A, Levesque, M J, Khosravi, A, Papanastasiou-Diamandi, G M, Clark, E P, Diamandis   +5 more
openaire   +2 more sources

Insulin-like Growth Factor Binding Protein 3 in Inflammatory Bowel Disease

Digestive Diseases and Sciences, 2005
Epithelial cell growth regulation has been reported to be altered in inflammatory bowel disease (IBD) patients. The cell growth regulatory factor, insulin-like growth factor binding protein 3 (IGFBP-3), may be partly responsible for this phenomenon. So far, IGFBP-3 levels have been assessed as values of total protein, which is a sum of bioactive intact
Kirman, Irena, Whelan, Richard Larry, Jain, Suvinit, Nielsen, Sara Elsøe, Seidelin, Jakob Benedict, Nielsen, Ole Haagen   +5 more
openaire   +2 more sources

Insulin-Like Growth Factor Binding Protein-3 Inhibits Colitis-Induced Carcinogenesis

Diseases of the Colon & Rectum, 2007
Chronic inflammation in the setting of inflammatory bowel disease is thought to result in altered epithelial cell growth regulation and ultimately carcinogenesis. This loss in cell growth regulation may be partially caused by a decrease in circulating intact insulin-like growth factor binding protein-3 (IFGB-3) as a result of chronic inflammation. This
A, Belizon, E, Balik, I, Kirman, H, Remotti, N, Ciau, S, Jain, R L, Whelan   +6 more
openaire   +2 more sources

Serum Insulin-Like Growth Factor Type 1, Insulin-Like Growth Factor-Binding Protein-1, and Insulin-Like Growth Factor-Binding Protein-3 Concentrations in Patients with Thyroid Dysfunction

Thyroid, 2001
Thyroid hormones play a role in the regulation of insulin-like growth factor type 1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) expression, and both IGF-1 and IGFBPs have been shown to be related to the function and growth of the thyroid. Our aim was to evaluate serum concentrations of IGF-1, IGFBP-1, and IGFBP-3 in patients with
P, Iglesias, C, Bayón, J, Méndez, P G, Gancedo, C, Grande, J J, Diez   +5 more
openaire   +2 more sources

Regulation and Actions of Insulin-Like Growth Factor Binding Protein-3

1991
Binding proteins for the insulin-like growth factors (IGFs), first described 15 years ago, are now recognized as playing important roles as carriers of IGFs in the circulation, and modulators of IGF actions on target cells 1. Three distinct structural classes of IGF binding protein (IGFBP) have been identified on the basis of cDNA cloning 2–6, and at ...
R C, Baxter, J L, Martin
openaire   +2 more sources

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

The Lancet, 2004
A. Renehan, M. Zwahlen, C. Minder, S. O'dwyer, S. Shalet, M. Egger   +5 more
semanticscholar   +1 more source

Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma.

Journal of Clinical Endocrinology and Metabolism, 1992
Pinchas Cohen, H. Graves, D. Peehl, Mehdi Kamarei, L. Giudice, R. Rosenfeld   +5 more
semanticscholar   +1 more source

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Responses of total and free insulin-like growth factor-I and insulin-like growth factor binding protein-3 after resistance exercise and training in elderly subjects.

Acta Physiologica Scandinavica, 1999
S. Bermon, P. Ferrari, P. Bernard, S. Altare, C. Dolisi   +4 more
semanticscholar   +1 more source

Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease.

Journal of Endocrinology, 1994
Pinchas Cohen, D. Peehl, H. Graves, R. Rosenfeld   +3 more
semanticscholar   +1 more source