Results 41 to 50 of about 498,256 (338)

Insulin-like growth factor-I and its binding proteins in healthy mothers and their newborns [PDF]

Einstein (São Paulo), 2004
Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternalserum and in cord blood of two groups of newborns with differentbirth weights.
Rosanna Velleca Lima, Daniel Giannella Neto, Conceição Aparecida de Mattos Segre, Saul Goldenberg   +3 more
doaj  

Serum IGF-1 in patients with rheumatoid arthritis: correlation with disease activity

BMC Research Notes, 2022
Objective Insulin-like growth factor (IGF)-1 participates in modulating immunity and inflammation. Its bioactivity is controlled by six IGF-binding proteins (IGFBP-1 to IGFBP-6).
Hanna Lee, Young Sun Suh, Sang-Il Lee, Yun-Hong Cheon, Mingyo Kim, Hae Sook Noh, Hyun-Ok Kim   +6 more
doaj   +1 more source

Nuclear Import of Insulin-like Growth Factor-binding Protein-3 and -5 Is Mediated by the Importin β Subunit*

Journal of Biological Chemistry, 2000
Although insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 are known to modulate cell growth by reversibly sequestering extracellular insulin-like growth factors, several reports have suggested that IGFBP-3, and possibly also IGFBP-5, have
L. Schedlich, Sophie Le Page, S. Firth, L. Briggs, D. Jans, R. Baxter   +5 more
semanticscholar   +1 more source

Late Effects of Disturbed IGF Signaling in Congenital Diseases. [PDF]

, 2007
The biologic effects of insulin-like growth factor-1 (IGF-1) are mediated by specific cell surface receptors. IGF-1 binding to the extracellular -subunits activates the tyrosine kinase intrinsic to the cytoplasmic portion of the IGF-1 receptor ...
Cianfarani S, Geremia C, Germani D, Maiorana A, Puglianiello A   +4 more
core   +1 more source

Role of Insulin-like Growth Factor Binding Protein 3 as a Diagnostic Marker of Growth Hormone in Patients with Acromegaly

Mìžnarodnij Endokrinologìčnij Žurnal, 2013
The paper studied the levels IGFBP-3 in patients with acromegaly, received different therapies. The findings showed that patients with acromegaly after surgical removal of a pituitary tumor, as well as after radiation therapy, the most sensitive ...
A.O. Kholikova
doaj   +1 more source

Malnutrition in children associated with low insulin-like growth factor binding protein-3 (IGFBP-3) levels

Gaceta Sanitaria, 2021
Objective: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status.
Dwi Ayu Rahmawati, Aminuddin Aminuddin, Firdaus Hamid, Prihantono Prihantono, Burhanuddin Bahar, Veni Hadju   +5 more
doaj   +1 more source

Insulin-Like Growth Factor I, Insulin-like Growth factor Binding Protein 3, and Atrial Fibrillation in the Elderly [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2013
Insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3) are involved in oxidative stress and atherosclerosis; however, the relationship between the IGF-I system and atrial fibrillation (AF) is not known. The objective of this analysis was to assess, the relationship between IGF-I and IGFBP-3 serum levels and AF ...
Emmanuelle, Duron, Jean-Sébastien, Vidal, Benoît, Funalot, Nadège, Brunel, Cécile, Viollet, Marie-Laure, Seux, Jean-Marc, Treluyer, Jacques, Epelbaum, Yves Le, Bouc, Olivier, Hanon   +9 more
openaire   +2 more sources

IGFBP-3 inhibits Wnt signaling in metastatic melanoma cells. [PDF]

, 2016
In previous works, we have shown that insulin-like growth factor-binding protein-3 (IGFBP-3), a tissue and circulating protein able to bind to IGFs, decreases drastically in the blood serum of patients with diffuse metastatic melanoma.
Londei, Paola, Martella, M, Naspi, A, Panasiti, Vincenzo, Polinari, Dorina, Rosa Alba, R, Sancillo, L, Zingariello, M   +7 more
core   +1 more source

Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats

International Brazilian Journal of Urology, 2016
Purpose To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats.
Zhang-Yan Zhou, Guang-Jun Zhong, Shao-Ping Cheng, Hui Huang, Jing Wang, Hui Pan, Chang-Mao Liu, Cheng Xing, Ya-Ling Sun, Rong-Hua Liu, Fei-Li   +10 more
doaj   +1 more source

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, Pirianov, G
core   +2 more sources