Results 111 to 120 of about 411,109 (307)
Regulation of multiple insulin-like growth factor binding protein genes by 1α,25-dihydroxyvitamin D(3) [PDF]
, 2005 Recently, insulin-like growth factor binding proteins (IGFBPs) have been found to be primary mediators of the anti-proliferative actions of the nuclear hormone 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)], but dependent on cellular context IGFBPs can ...
Carlberg, Carsten +3 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen +7 more
wiley +1 more source
BMC Gastroenterology, 2019 Background Children in poor areas show significant growth retardation that does not improve with an adequate supply of energy and nutrients, which may be related to asymptomatic intestinal infection caused by poor sanitation. Our objective was to explore
Xiaoyang Sheng +4 more
doaj +1 more source
Insulin-like growth factor binding protein-1 and insulin in polycystic ovary syndrome: a systematic review and meta-analysis. [PDF]
Front Endocrinol (Lausanne), 2023 Jin Y +13 more
europepmc +1 more source
Cancer Cell-Derived Clusterin Modulates the Phosphatidylinositol 3'-Kinase-Akt Pathway through Attenuation of Insulin-Like Growth Factor 1 during Serum Deprivation [PDF]
, 2014 Cancer cells in their respective microenvironments must endure various growth-constraining stresses. Under these conditions, the cancer cell-derived factors are thought to modulate the signaling pathways between cell growth and dormancy.
Hattori, Hidenori +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases
Molecular MedicineThe oncofetal mRNA-binding protein IGF2BP1 belongs to a conserved family of RNA-binding proteins. It primarily promotes RNA stability, regulates translation and RNA localization, and mediates gene expression through its downstream effectors.
Shuangping Ma, Yiran Qin, Wenjie Ren
doaj +1 more source
Research progress of IGF-1 and IGFBP-3 in type 2 diabetes and its microvascular complications
生物医学转化The prevalence of type 2 diabetes mellitus (T2DM) and its microvascular complications is increasing year by year, posing a serious threat to human health and greatly increasing the socioeconomic burden.
Huang Shuting, Yang Yang
doaj +1 more source
BMC Endocrine Disorders, 2018 Background Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP).
Hua-Pin Chang +3 more
doaj +1 more source
Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells [PDF]
, 2017 Testosterone by promoting different metabolic pathways contributes to short-term homeostasis of skeletal muscle, the largest insulin-sensitive tissue and the primary site for insulin-stimulated glucose utilization.
Antinozzi, Cristina +8 more
core +2 more sources