Results 111 to 120 of about 241,190 (311)

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases

Molecular Medicine
The oncofetal mRNA-binding protein IGF2BP1 belongs to a conserved family of RNA-binding proteins. It primarily promotes RNA stability, regulates translation and RNA localization, and mediates gene expression through its downstream effectors.
Shuangping Ma, Yiran Qin, Wenjie Ren
doaj   +1 more source

Research progress of IGF-1 and IGFBP-3 in type 2 diabetes and its microvascular complications

生物医学转化
The prevalence of type 2 diabetes mellitus (T2DM) and its microvascular complications is increasing year by year, posing a serious threat to human health and greatly increasing the socioeconomic burden.
Huang Shuting, Yang Yang
doaj   +1 more source

Linear growth failure induced by systemic inflammation inhibiting IGF-1/IGFBP axis in rats with asymptomatic colitis

BMC Gastroenterology, 2019
Background Children in poor areas show significant growth retardation that does not improve with an adequate supply of energy and nutrients, which may be related to asymptomatic intestinal infection caused by poor sanitation. Our objective was to explore
Xiaoyang Sheng, Xueqing Sun, Feng Li, Junli Wang, Jingqiu Ma   +4 more
doaj   +1 more source

Increased Colocalization and Interaction Between Decidual Protein Kinase A and Insulin-like Growth Factor-Binding Protein-1 in Intrauterine Growth Restriction. [PDF]

J Histochem Cytochem, 2022
Gupta MB, Biggar KK, Li C, Nathanielsz PW, Jansson T.   +4 more
europepmc   +1 more source

The role of hepatocyte growth factor/scatter factor in hepatoblastoma and hepatocellular carcinoma progression [PDF]

, 2006
Hepatocyte growth factor/scatter factor (HGF/SF) is a ubiquitously expressed molecule that elicits pleiotropic functions on epithelial cells, including mitogenic, motogenic, differentiating, angiogenic, and morphogenic effects. The receptor for HGF/SF is
Grotegut, Stefan
core   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Does isotretinoin have an effect on glucose metabolism, insulin growth factor-1 and insulin-like growth factor-3 binding protein?

Przegląd Dermatologiczny, 2022
Esra Dogan
doaj   +1 more source

Clinical Characterization of the Expression of Insulin-Like Growth Factor Binding Protein 1 and Tumor Immunosuppression Caused by Ferroptosis of Neutrophils in Non-Small Cell Lung Cancer. [PDF]

Int J Gen Med, 2023
Wang Y, Xing L, Deng L, Wang X, Xu D, Wang B, Zhang Z.   +6 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding. [PDF]

Int J Mol Sci, 2022
O'Neill LM, Phang YX, Liu Z, Lewis SA, Aljohani A, McGahee A, Wade G, Kalyesubula M, Simcox J, Ntambi JM.   +9 more
europepmc   +1 more source