Results 281 to 290 of about 411,109 (307)

Insulin‐like growth factor binding protein‐1 at mouse neuromuscular synapses

Synapse, 1994
AbstractThe insulin‐like growth factor (IGF) signaling system includes the growth factors and their cell surface receptors, along with circulating IGF binding proteins (IGFBPs) that may alter and modulate the action of these neurotrophic hormones. These IGFBPs, along with IGFs and receptors, have been detected in various tissues including the brain. In
J, Ma, S X, Yang, G J, Ho, B W, Festoff
openaire   +2 more sources

Interaction between insulin-like growth factor-I and insulin-like growth factor-binding proteins in TC-1 stromal cells

Journal of Endocrinology, 1996
Abstract IGF-I and -II play an important role in regulating bone formation. Bone marrow stromal cells, particularly those with osteoblast-like features, may act in concert with osteoblasts to increase IGF-I and -II levels in the bone microenvironment. Local bioavailability of IGFs, however, is modulated by IGF binding proteins (IGFBPs). We have
P, Grellier, D, Feliers, D, Yee, K, Woodruff, S L, Abboud   +4 more
openaire   +2 more sources

Regulation of Insulin-Like Growth Factor–Binding Protein-1 in Rat Serum

Diabetes, 1994
Previous studies support a role for insulin-like growth factor–binding protein-1 (IGFBP-1) in modulating insulin-like growth factor (IGF) availability for glucose homeostasis. We have developed a radioimmunoassay (RIA) for rat IGFBP-1 (rIGFBP-1) and have examined the regulation of circulating levels by nutritional and hormonal status.
M S, Lewitt, H, Saunders, J L, Phyual, R C, Baxter   +3 more
openaire   +2 more sources

Growth hormone suppression of insulin-like growth factor binding protein-1 promoter activity

Molecular and Cellular Endocrinology, 1999
Hepatic transcription of insulin-like growth factor binding protein-1 (IGFBP-1) is rapidly downregulated by growth hormone (GH) which is also known to induce expression of c-fos and c-jun. Co-expression of c-fos or c-jun in rat hepatocytes, individually or together, suppresses IGFBP-1 promoter activity by approximately 60%.
X, Lu, Z, Shi, L J, Murphy
openaire   +2 more sources

Serum Insulin, Insulin-Like Growth Factor-I, and Insulin-Like Growth Factor Binding Protein-1 in Women Who Develop Preeclampsia

Obstetrics & Gynecology, 2001
To determine whether second-trimester serum concentrations of insulin, insulin-like growth factor-I (IGF-I), and insulin-like growth factor binding protein-1 (IGFBP-1) were altered in women before they developed clinical signs of preeclampsia.A nested case-control study used serum obtained during second-trimester pregnancies from 12 women who developed
W A, Grobman, R R, Kazer
openaire   +2 more sources

Does hypoxia only influence insulin‐like growth factor‐1 through insulin‐like growth factor binding protein‐1?

Journal of Obstetrics and Gynaecology Research, 2014
Miao, Sun, Qian, Li
openaire   +2 more sources

Cancer treatment and survivorship statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Kimberly D Miller, Leticia M Nogueira, Angela B Mariotto   +2 more
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Insulin-Like Growth Factor Binding Protein-1

Seminars in Reproductive Medicine, 1992
openaire   +1 more source

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly