Results 191 to 200 of about 239,986 (298)

Insulin-like growth factor-binding protein-3 is induced by tamoxifen and fulvestrant and modulates fulvestrant response in breast cancer cells. [PDF]

Front Oncol
Flynn KL, Zheng Y, Sowers JY, Masangya NJT, Houston KD.   +4 more
europepmc   +1 more source

Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3): Unraveling the Role in Mediating IGF-Independent Effects Within the Cell. [PDF]

Front Cell Dev Biol, 2020
Varma Shrivastav S, Bhardwaj A, Pathak KA, Shrivastav A.   +3 more
europepmc   +1 more source

Versatile DNA‐Functionalized Biohybrid Hydrogel Platforms for Electrothermally Activated On‐Demand Payload Release

Advanced Science, EarlyView.
A DNA‐functionalized biohybrid hydrogel is developed by integrating Cu‐mediated nucleic acid microflowers into a thermoresponsive matrix, enabling electrothermally triggered, on‐demand payload release. The platform offers spatiotemporally controllable therapeutic delivery with promising applications in precision oncology, neural regulation, and chronic
Mengqiu Sun, Zhenshuai Tang, Jia Zhang, Rui Song, Wei Luo, Juan Huang, Jincheng Zeng, Zhen He, Hao Zhang   +8 more
wiley   +1 more source

Paracrine senescence of human endometrial mesenchymal stem cells: a role for the insulin-like growth factor binding protein 3. [PDF]

Aging (Albany NY), 2020
Vassilieva I, Kosheverova V, Vitte M, Kamentseva R, Shatrova A, Tsupkina N, Skvortsova E, Borodkina A, Tolkunova E, Nikolsky N, Burova E.   +10 more
europepmc   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Insulin-like Growth Factor 1, but Not Insulin-Like Growth Factor-Binding Protein 3, Predicts Central Precocious Puberty in Girls 6-8 Years Old: A Retrospective Study.

Horm Res Paediatr, 2021
Escagedo PD, Deal CL, Dwyer AA, Hauschild M.   +3 more
europepmc   +1 more source

Insulin-Like Growth Factor Binding Protein-3: Insulin-Like Growth Factor Independence Comes of Age [PDF]

Endocrinology, 2006
openaire   +1 more source

The functional consequences of the interactions between insulin-like growth factors (IGFs), insulin-like growth factor binding proteins (IGFBPs) and vitronectin (VN) and their involvement in skin

, 2006
The insulin-like growth factor (IGF) system plays an important role in a number of disease states, such as cancer, and has also been implicated in wound and burn healing processes.
Hyde, Carolyn Elizabeth
core  

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source