Results 301 to 310 of about 463,657 (378)

N6-methyladenosine reader <i>IGF2BP2</i> regulates <i>NIPSNAP1</i>-mediated mitophagy and mitochondrial dynamics to alleviate hepatic ischemia-reperfusion injury. [PDF]

World J Gastroenterol
Guo SS, Zhao Y, Hu Y, Wang XY, Zhao XZ, Zhong PY, Luan QR, Wang ZC, Yao JH.   +8 more
europepmc   +1 more source

Engineered Anti‐Senescence Trachea With Post‐Transplanted Regenerative Homeostasis

Advanced Science, EarlyView.
Bioengineered trachea undergoes post‐transplanted senescence, which is found in this study for the first time. Hebe‐ET is designed with dual anti‐senescence strategies: fiber‐film scaffold in cartilage rings for close‐packed cell interaction, and quercetin‐loaded fibrous rings for immune modulation.
Ziyin Pan, Hai Tang, Lanlan Wang, Qingfeng Bai, Yi Chen, Runfeng Cao, Weikang Lin, Lei Wang, Yulong Hu, Guofang Zhao, Minglei Yang, Weiyan Sun, Kun Zhang, Dawei Li, Chang Chen   +14 more
wiley   +1 more source

Impacts of commercial bile acids on growth performance, immune responses and expression genes of lipid metabolism in Nile tilapia fingerlings Oreochromis niloticus. [PDF]

Sci Rep
Marzouk Y, Zaki MA, Nour AM, Mehrim AI, Khalil HS.   +4 more
europepmc   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Insulin-Like Growth Factor Binding Protein, Acid-Labile Subunit Serum Level During the Acute and Convalescent Stage of SARS-CoV-2 Infection Depicted in a Longitudinal Study of 72 Patients During the First Wave of Pandemic. [PDF]

J Multidiscip Healthc
Gad H, Mahmoud MA, Antar M, Sayed Ahmed A, Laudanski K.   +4 more
europepmc   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Plasma Insulin-Like Growth Factor-Binding Protein-2 Levels Predict Severe Septic Acute Kidney Injury: A Mendelian Randomization Analysis. [PDF]

Cureus
Zhao B, Zhao Z, Wang Z.
europepmc   +1 more source

Aerobic exercise-induced changes in fluid biomarkers in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Luthra NS, Mehta N, Munoz MJ, Fantuzzi G, Lamotte G, Haus JM, McFarland NR, Tansey MG, Gonzalez-Latapi P, Caraveo G, Kang UJ, Corcos DM.   +11 more
europepmc   +1 more source

Tyrosine kinase inhibitors in Ewing's sarcoma: a systematic review. [PDF]

BMC Cancer
Assi A, Farhat M, Mohanna R, Hachem MCR, Zalaquett Z, Aoun M, Farraj SA, Daher M, Sebaaly A, Kourie HR.   +9 more
europepmc   +1 more source