Results 281 to 290 of about 242,514 (346)

Insulin Levels After Portal and Systemic Insulin Infusion Differ in a Dose-Dependent Fashion

Hormone and Metabolic Research, 1998
The role of the liver in the regulation of systemic insulin levels is not well understood. The reported extraction rates vary between 0 to 85%, and extraction of a constant fraction of 50% of the portally delivered insulin is generally assumed. In the present study, we have investigated the role of the liver in the regulation of systemic insulin levels
de Vos, P., de Haan, Bart, Vegter, D., Hillebrands, J.L., Strubbe, J.H., Bruggink, Jan, Schilfgaarde, R. van   +6 more
openaire   +3 more sources

Continuous subcutaneous insulin infusion systems

Postgraduate Medicine, 1983
Although continuous subcutaneous insulin infusion (CSII) is not presently the most feasible method of insulin delivery for most type I diabetic patients, unquestionably it is a major therapeutic advance in recent efforts to normalize blood glucose levels in such patients.
openaire   +2 more sources

Programming of an open-loop system for I.V. insulin infusion in insulin-dependent diabetes

Acta Diabetologica Latina, 1980
The blood glucose of 10 stable unstressed uncomplicated insulin-dependent diabetics (age: 39 ± 4 years; duration of diabetes: 11 ± 1 years) was controlled by a preprogrammed open-loop system of i.v. insulin infusion during two randomized consecutive days. Individual constant basal insulin rates were determined by adapting the rate of the pump to obtain
J, Mirouze, J L, Selam, T C, Pham, D, Chenon   +3 more
openaire   +2 more sources

A semi‐closed loop computer‐assisted insulin infusion system

Medical Journal of Australia, 1984
Closed loop insulin delivery systems are impractical for widespread hospital use. Thus, a semi-closed loop computer-assisted insulin infusion system (CAIIS) was developed for the intravenous delivery of insulin. In its basal program, insulin delivery is determined by blood glucose measurements at intervals of three hours, while the open-loop meal ...
Donald J. Chisholm, Edward W. Kraegen, David J. Bell, David R. Chipps   +3 more
openaire   +1 more source

Clinical application of pre-programmed insulin infusion: continuous subcutaneous insulin therapy with a portable infusion system.

Hormone and metabolic research. Supplement series, 1980
Strict control of blood glucose was achieved by continuous subcutaneous insulin infusion with a specially adapted Mill Hill Infuser for 3-4 days. This led to normalisation of some of the intermediary metabolites. In a few patients, subcutaneous infusions have been carried out for periods up to 3 months with home monitoring of blood glucose, without ...
J C, Pickup, G C, Viberti, H, Keen, J A, Parsons, K G, Alberti   +4 more
openaire   +1 more source

Integrated catheter system for continuous glucose measurement and simultaneous insulin infusion

Biosensors and Bioelectronics, 2015
A new measurement system enables combination of continuous glucose monitoring (CGM) and insulin infusion. A sensor system comprising an optical glucose biosensor and an optical oxygen sensor is integrated into the insulin infusion catheter of an insulin pump.
Barbara Nacht, Christoph Larndorfer, Stefan Sax, Sergey M. Borisov, Martin Hajnsek, Frank Sinner, Emil J.W. List-Kratochvil, Ingo Klimant   +7 more
openaire   +2 more sources

Effect of glucose-insulin-potassium infusion on the human conduction system

The American Journal of Cardiology, 1974
His bundle electrograms were performed in 21 patients with organic heart disease. Recordings were made at various rates utilizing right atrial pacing. A mixture containing 50 g of glucose, 10 mEq of potassium and 20 units of insulin was given intravenously over 10 minutes to 10 subjects.
L, Gould, C V, Reddy, R F, Gomprecht
openaire   +2 more sources

Technology of pre-programmable insulin delivery systems: continuous subcutaneous insulin infusion.

Hormone and metabolic research. Supplement series, 1980
Dual-rate continuous subcutaneous insulin infusion was performed with a specially adapted Mill Hill Infuser. The infuser delivers 2 rates, a slow rate of ca. 50 microliter/h and an eightfold higher rate, designed to cover the increased requirement during meals.
J C, Pickup, H, Keen, J A, Parsons, K G, Alberti   +3 more
openaire   +1 more source

Substitution of Islet-Cell Function With “Open-Loop” Insulin Infusion Systems

1979
It is still not entirely clear to what extent the late complications of diabetes depend upon the quality of metabolic control. However, more recent studies have provided strong arguments for a causal relationship (1,2). It also became increasingly evident how inadequate in fact is our therapy with diet and subcutaneous insulin injections (3).
K D, Hepp, R, Renner, M, Franetzki, H, Mehnert   +3 more
openaire   +2 more sources

Preprogrammed insulin infusion with a portable pump system.

Hormone and metabolic research. Supplement series, 1980
A glucose-controlled insulin infusion system (Biostator) was used to determine patient insulin requirement for clinical evaluation of a portable pump system (technical development by Siemens AG). Results from 6 insulin-dependent diabetics with respect to quality of control, carbohydrate/insulin ratio, and insulin requirement are shown.
K, Irsigler, H, Kritz, L, Kaspar, J, Brändle, W, Koller, M, Franetzki   +5 more
openaire   +1 more source