Results 41 to 50 of about 659,864 (298)

The role of sickness absence diagnosis for the risk of future inpatient- or specialized outpatient care in a Swedish population-based twin sample

BMC Public Health, 2021
Background Studies of consequences of sickness absence such as health and well-being have been rare whereas risk factors for sickness absence have been studied extensively.
Annina Ropponen, Mo Wang, Jurgita Narusyte, Sanna Kärkkäinen, Victoria Blom, Pia Svedberg   +5 more
doaj   +1 more source

High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin   +10 more
wiley   +1 more source

The predictive role of sickness absence spell durations in associations with inpatient- and specialized outpatient care among a population-based Swedish twin sample

BMC Health Services Research, 2021
Background The associations between a sickness absence spell duration and patient care have been rarely studied. An assumption is that associations would differ by spell duration and by the patient care type, inpatient- or specialized outpatient, due to ...
Annina Ropponen, Mo Wang, Jurgita Narusyte, Sanna Kärkkäinen, Victoria Blom, Pia Svedberg   +5 more
doaj   +1 more source

Risk Corridors and Reinsurance in Health Insurance Marketplaces: Insurance for Insurers [PDF]

American Journal of Health Economics, 2016
Health Insurance Marketplaces established by the Affordable Care Act implement reinsurance and risk corridors. Reinsurance limits insurer costs associated with specific individuals, while risk corridors protect against aggregate losses. Both tighten the insurer's distribution of expected costs. This paper compares the economic costs and consequences of
Timothy J. Layton, Thomas G. McGuire, Anna D. Sinaiko   +2 more
openaire   +4 more sources

Durable B‐Cell Impairment While Sparing IgA B Cells After Ocrelizumab Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Ocrelizumab (OCR), a humanized anti‐CD20 monoclonal antibody, is highly efficient in relapsing–remitting multiple sclerosis (RR‐MS). We assessed early cellular B‐cell profiles in patients prior to OCR treatment, on OCR treatment, and after 15 months of therapy discontinuation.
Alexandra Garcia, Stephane Rodriguez, Emilie Dugast, Christine Lebrun‐Frenay, Eric Thouvenot, Jérôme de Sèze, Emmanuelle Le Page, Sandra Vukusic, Inès Doghri, Eric Berger, Olivier Casez, Pierre Labauge, Aurélie Ruet, Catarina Raposo, Fabienne Le Frère, Arnaud B. Nicot, Sandrine Wiertlewski, Pierre‐Antoine Gourraud, Laure Michel, Laureline Berthelot, David‐Axel Laplaud   +20 more
wiley   +1 more source

Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad, Lili Zhou, Brian Manolovitz, Negar Asdaghi, Hannah Gardener, Hao Ying, Carolina M. Gutierrez, Angus Jameson, David Rose, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Sebastian Koch, Jose G. Romano, Tatjana Rundek, Ayham Alkhachroum   +15 more
wiley   +1 more source

Real-world effectiveness of long-acting injections for reducing recurrent hospitalizations in patients with schizophrenia

Annals of General Psychiatry, 2020
Background The comparative effectiveness of antipsychotic long-acting injections (LAIs) and oral medication is not clear due to various methodological problems.
Hye Ok Kim, Gi Hyeon Seo, Boung Chul Lee
doaj   +1 more source

Constructing a Real-Time Prescription Drug Monitoring System [PDF]

Healthcare Informatics Research, 2016
ObjectivesThe objective of this investigation was to demonstrate the possibility of the construction of a real-time prescription drug monitoring system (PDMOS) using data from the nationwide Drug Utilization Review (DUR) system in Korea.MethodsThe DUR ...
Young-Taek Park, Youn Tae Lee, Emmanuel C. Jo   +2 more
doaj   +1 more source

Real World Effectiveness and Tolerability of Novel Monoclonal Antibodies and Rituximab for NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this multicenter retrospective cohort study of 135 people with aquaporin‐4 IgG+ neuromyelitis optica spectrum disorder (NMOSD), some of whom were exposed to multiple therapies, we evaluated the effectiveness and tolerability of rituximab (n = 111) and novel monoclonal antibodies (nMAbs): eculizumab (n = 9), inebilizumab (n = 23), and ...
Zarmina Javed, Mengke Du, Mary Rensel, Le H. Hua, Carrie M. Hersh, Justin R. Abbatemarco, Devon S. Conway, Daniel Ontaneda, Jeffrey A. Cohen, Amy Kunchok   +9 more
wiley   +1 more source

Identification and Validation of a Malignant Cell Subset Marker-Based Polygenic Risk Score in Stomach Adenocarcinoma Through Integrated Analysis of Bulk and Single-Cell RNA Sequencing Data

Frontiers in Cell and Developmental Biology, 2021
Objectives: The aim of the present study was to construct a polygenic risk score (PRS) for poor survival among patients with stomach adenocarcinoma (STAD) based on expression of malignant cell markers.Methods: Integrated analyses of bulk and single-cell ...
Qiyuan Zou, Yufeng Lv, Zuhuan Gan, Shulan Liao, Zhonghui Liang   +4 more
doaj   +1 more source