Results 201 to 210 of about 4,654 (265)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Spin-polarized light-emitting diodes based on CrI₃ operating without external spin injection. [PDF]

Nat Commun
Lu CC, Chang LW, Li WQ, Chen PL, Lin YJ, Pan KH, Kuo C, Liu CH.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

β-Fractional [Formula: see text]-dimensional generalized KP model: nonlinear dynamical behaviors, analytical wave structures, bifurcation, and sensitivity analysis. [PDF]

Sci Rep
Demirbilek U, Danladi A, Akbulut A, Boulaaras S, Ahmed KK.   +4 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Nonlinear SPDEs and Maximal Regularity: An Extended Survey. [PDF]

Nonlinear Differ Equ Appl
Agresti A, Veraar M.
europepmc   +1 more source

Exploration of the soliton solutions of the (n+1) dimensional generalized Kadomstev Petviashvili equation using an innovative approach. [PDF]

Sci Rep
Kopçasız B, Sağlam FNK, Bulut H, Radwan T.   +3 more
europepmc   +1 more source

Notes on the Jellinek-Berry Thermostated Ideal Gas. [PDF]

J Stat Phys
Butler LT, Sharifi A.
europepmc   +1 more source

Exact soliton, lump, and breather solutions of the (3 + 1)-dimensional Jimbo-Miwa equation via the bilinear neural network method. [PDF]

Sci Rep
Hussein HH, Mekawey H, Elsheikh A.
europepmc   +1 more source

Nonlinear Monte Carlo Methods with Polynomial Runtime for Bellman Equations of Discrete Time High-Dimensional Stochastic Optimal Control Problems. [PDF]

Appl Math Optim
Beck C, Jentzen A, Kleinberg K, Kruse T.
europepmc   +1 more source