Results 81 to 90 of about 8,186,626 (298)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Alternate approach to no integrability field theory

open access: yesMathematical and Computer Modelling, 1989
This is another paper in a series which illustrates that foregoing the rules of traditional calculus opens up a realm of possibilities. We study the ''aesthetic field theory'', although the techniques are more general. We introduce a new integration procedure which is consistent with aesthetic principles.
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The complex sine-Gordon model on a half line [PDF]

open access: yes, 2003
In this thesis, we study the complex sine-Gordon model on a half line. The model in the bulk is an integrable (l+1) dimensional field theory which is U(1) gauge invariant and comprises a generalisation of the sine-Gordon theory.
Tzamtzis, Georgios
core  

Integrable field theories from Poisson algebras [PDF]

open access: yes, 1991
New integrable 1 + 1 dimensional classical field theories are found that include infinite dimensional analogues of N-particle Toda-and Calogero-Moser systems, as well as non-relativistic theories with an interaction that is polynomial in the first ...
Theisen, Stefan   +5 more
core   +1 more source

P T $$ \mathcal{P}\mathcal{T} $$ deformation of Calogero-Sutherland models

open access: yesJournal of High Energy Physics, 2019
Calogero-Sutherland models of N identical particles on a circle are deformed away from hermiticity but retaining a P T $$ \mathcal{P}\mathcal{T} $$ symmetry.
Francisco Correa, Olaf Lechtenfeld
doaj   +1 more source

On the hydrodynamics of unstable excitations

open access: yesJournal of High Energy Physics, 2020
The generalized hydrodynamic (GHD) approach has been extremely successful in describing the out-of-equilibrium properties of a great variety of integrable many-body quantum systems.
Olalla A. Castro-Alvaredo   +3 more
doaj   +1 more source

On Cherednik and Nazarov-Sklyanin large N limit construction for integrable many-body systems with elliptic dependence on momenta

open access: yesJournal of High Energy Physics, 2021
The infinite number of particles limit in the dual to elliptic Ruijsenaars model (coordinate trigonometric degeneration of quantum double elliptic model) is proposed using the Nazarov-Sklyanin approach.
A. Grekov, A. Zotov
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Symmetry methods for integrable systems [PDF]

open access: yes, 1996
This thesis discusses various properties of a number of differential equations which we will term "integrable". There are many definitions of this word, but we will confine ourselves to two possible characterisations — either an equation can be ...
Mulvey, Joseph Anthony, Mulvey, J.A
core  

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