Results 91 to 100 of about 24,425,209 (308)

A new hierarchy of integrable system of 1+2 dimensions: from Newton's law to generalized Hamiltonian system. Part II

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2006
The Hamiltonian equation provides us an alternate description of the basic physical laws of motion, which is used to be described by Newton's law.
Xuncheng Huang, Guizhang Tu
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Systèmes dynamiques algébriquement complètement intégrables et géométrie

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2015
In this paper I present the basic ideas and properties of the complex algebraic completely integrable dynamical systems. These are integrable systems whose trajectories are straight line motions on complex algebraic tori (abelian varieties). We make, via
Lesfari A.
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Integrable Couplings and Two-Dimensional Unital Algebras

open access: yesAxioms
The paper aims to demonstrate that a linear expansion in a unital two-dimensional algebra can generate integrable couplings, proposing a novel approach for their construction. The integrable couplings presented encompass a range of perturbation equations
Wen-Xiu Ma
doaj   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

NEW EXAMPLE OF FINITE-DIMENSIONAL REDUCTION OF A DISCRETE CHAIN OF THE TODA CHAIN TYPE

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. Integrable discrete equations considered in the framework of the numerical study of their continuous analogs. Same time continuous equations obtained using the limit from the discrete systems.
T. G. Kazakova, R. R. Sattarova
doaj   +1 more source

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