Results 101 to 110 of about 237,485 (323)
Integration of BPM Systems [PDF]
, 2010 New technologies have emerged to support the global economy where for instance suppliers, manufactures and retailers are working together in order to minimise the cost and\ud maximise efficiency. One of the technologies that has become a buzz word for many businesses is business process management or BPM.
Ma, Chaoying +4 more
openaire +3 more sources
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Discretisations of constrained KP hierarchies [PDF]
, 2014 We present a discrete analogue of the so-called symmetry reduced or `constrained' KP hierarchy. As a result we obtain integrable discretisations, in both space and time, of some well-known continuous integrable systems such as the nonlinear Schroedinger ...
Hattori, Madoka, Willox, Ralph
core +2 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Journal of High Energy Physics, 2019 We present a new set of boundary conditions for General Relativity on AdS3, where the dynamics of the boundary degrees of freedom are described by two independent left and right members of the Gardner hierarchy of integrable equations, also known as the “
Emilio Ojeda, Alfredo Pérez
doaj +1 more source
, 2021 Human-systems integration (HSI) denotes a possible evolution of two disciplines, that are Human Factors and Ergonomics (HFE) and Human-Computer Interaction (HCI), that led to Human-Centered Design (HCD), more specifically within the field of Systems Engineering (SE). HSI pragmatically considers the Technology, Organizations, and People (TOP) Model that
openaire +3 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Physics Letters A, 2008 $K^2 S^2 T [5]$ recently derived a new 6$^{th}$-order wave equation $KdV6$: $(\partial^2_x + 8u_x \partial_x + 4u_{xx})(u_t + u_{xxx} + 6u_x^2) = 0$, found a linear problem and an auto-B${\ddot{\rm{a}}}$ckclund transformation for it, and conjectured its integrability in the usual sense.
openaire +3 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source