Results 121 to 130 of about 237,485 (323)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Integrable Couplings and Two-Dimensional Unital Algebras

open access: yesAxioms
The paper aims to demonstrate that a linear expansion in a unital two-dimensional algebra can generate integrable couplings, proposing a novel approach for their construction. The integrable couplings presented encompass a range of perturbation equations
Wen-Xiu Ma
doaj   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

A 2+1-Dimensional Non-Isothermal Magnetogasdynamic System. Hamiltonian-Ermakov Integrable Reduction

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2012
A 2+1-dimensional anisentropic magnetogasdynamic system with a polytropic gas law is shown to admit an integrable elliptic vortex reduction when γ=2 to a nonlinear dynamical subsystem with underlying integrable Hamiltonian-Ermakov structure.
Hongli An, Colin Rogers
doaj   +1 more source

NEW EXAMPLE OF FINITE-DIMENSIONAL REDUCTION OF A DISCRETE CHAIN OF THE TODA CHAIN TYPE

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2020
Background. Integrable discrete equations considered in the framework of the numerical study of their continuous analogs. Same time continuous equations obtained using the limit from the discrete systems.
T. G. Kazakova, R. R. Sattarova
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Reduction of infinite dimensional equations

open access: yesElectronic Journal of Differential Equations, 2006
In this paper, we use the general Legendre transformation to show the infinite dimensional integrable equations can be reduced to a finite dimensional integrable Hamiltonian system on an invariant set under the flow of the integrable equations.
Zhongding Li, Taixi Xu
doaj  

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