Results 161 to 170 of about 245,746 (323)

The 3d Mixed BF Lagrangian 1-Form: A Variational Formulation of Hitchin's Integrable System. [PDF]

Commun Math Phys
Caudrelier V, Harland D, Singh AA, Vicedo B.   +3 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Integrable systems and group actions

Open Mathematics, 2014
Miranda Eva
doaj   +1 more source

Propagation of optical solitons and dispersive solitary wave structure in complex media to the nonlinear integrable system via computational technique. [PDF]

Sci Rep
Iqbal M, Faridi WA, Algethamie R, Aljohani A, El-Meligy M, Mohammad N, Alnowibet KA.   +6 more
europepmc   +1 more source

Situational analysis of community health systems in West Africa: Imperative to integrate social determinants of health [PDF]

Odame Emmanuel Ankrah, Houeto David, Balle Okpe, Ali Sani, Lokossou Virgil, Keita Kissi, Namam Pansau, Cardoso Placido, Issiaka Sombié, Usman Aishat B, Keita Namoudou, Agbla Felix, Melchior Aïssi   +12 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The SMART Framework: Integration of Citizen Science, Community-Based Participatory Research, and Systems Science for Population Health Science in the Digital Age

, 2019
Tarun Reddy Katapally
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

IEEE Transactions on Very Large Scale Integration (VLSI) Systems [PDF]

, 2019
Yong Lian, Amara Amara, Franco Maloberti, Eduard Alarcon, Myung Sunwoo, Andy Wu, Yehea Ismail, Yoshifumi Nishio, Guoxing Wang, Mophamad Sawan, Cecilia Metra, Leila De Floriani, Yervant Zorian, Fabrizio Lombardi, Dimitrios Serpanos, David Lomet, Riccardo Mariani, William Gropp, Kunio Uchiyama, John Walz, Elizabeth Burd, Melissa Russell, Joerg Henkel, Stefano Di, Bram Nauta, Jan Van Der Spiegel, Wanda Gass Treasurer, Emre Ayranci, Hideto Hidaka   +28 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source