Results 161 to 170 of about 237,485 (323)
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source
Integration in noncommutative systems [PDF]
openaire +2 more sources
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Integrable Hierarchy of Higher Nonlinear Schrödinger Type Equations
Addition of higher nonlinear terms to the well known integrable nonlinear Schrödinger (NLS) equations, keeping the same linear dispersion (LD) usually makes the system nonintegrable. We present a systematic method through a novel Eckhaus-Kundu hierarchy,
Anjan Kundu
doaj
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Dynamic Features of the Highly Excited Vibrational States of the HOCl Non-Integrable System Based on the Dynamic Potential and Lyapunov Exponent Approaches. [PDF]
Wang A, Fang C, Liu Y.
europepmc +1 more source
NUMERICAL INTEGRATION OF DYNAMIC NUCLEAR SYSTEMS EQUATIONS BY OPTIMUM INTEGRATING FACTORS.
P E Secker
openalex +2 more sources

