Results 191 to 200 of about 245,746 (323)

On the exploration of periodic wave soliton solutions to the nonlinear integrable Akbota equation by using a generalized extended analytical method. [PDF]

Sci Rep
Iqbal M, Liu J, Faridi WA, Alrashdi HD, Algethamie R, Aljohani A, Mohammad N, Alsubaie AS.   +7 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Optical closed form soliton structures for the Kuralay-II equation in nonlinear optical complex media. [PDF]

Sci Rep
Arshad A, Yasin MW, Saeed I, Ahmed N, Bittaye E, Baber MZ.   +5 more
europepmc   +1 more source

Editorial: Integration of oral health care within the healthcare system [PDF]

Sourabha Kumar Patro
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Exploration of nonclassical symmetries and exact solutions to the (4+1)-dimensional Boiti-Leon-Manna-Pempinelli equation. [PDF]

Sci Rep
Ur Rahman M, Akram S, Asif M.
europepmc   +1 more source

Painlevé Integrability And Shifted Nonlocal Reductions Of A Variable Coefficient Coupled HI Mkdv System [PDF]

Taylan Demir
openalex  

Integrating indigenous and modern water supply systems in rural South Africa [PDF]

Noxolo N. Ngema, Sijekula Mbanga, Adebiyi A. Adeniran, Emmanuel Kabundu   +3 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Photokinetics of Bimolecular Reactions: Analytically Solvable Rate Laws. [PDF]

Molecules
Maafi M.
europepmc   +1 more source