Existence and uniqueness theorems for impulsive fractional differential equations with the two-point and integral boundary conditions. [PDF]
Mardanov MJ, Mahmudov NI, Sharifov YA.
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Nonlinear fractional differential equations with $m$-point integral boundary conditions [PDF]
Tugba Senlik Cerdik +2 more
openalex +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Boundary value problems for fractional differential equations with three-point fractional integral boundary conditions [PDF]
Weerawat Sudsutad, Jessada Tariboon
openalex +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
High-order mixed-type differential equations with weighted integral boundary conditions
In this paper, we prove the existence and uniqueness of strong solutions for high-order mixed-type problems with weighted integral boundary conditions. The proof uses energy inequalities and the density of the range of the operator generated.
M. Denche, A. L. Marhoune
doaj
Successive iteration and positive solutions for a third-order boundary value problem involving integral conditions [PDF]
Huihui Pang, Wenyu Xie, Limei Cao
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Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Positive solutions for singular nonlocal boundary value problems involving nonlinear integral conditions [PDF]
Baoqiang Yan +2 more
openalex +1 more source

