Results 181 to 190 of about 780,879 (337)

Nonlocal boundary value problems of fractional order at resonance with integral conditions [PDF]

, 2017
Hai-E Zhang
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Frictional Heating During Sliding of Two Layers Made of Different Materials. [PDF]

Materials (Basel)
Topczewska K, Yevtushenko A, Zamojski P.
europepmc   +1 more source

Evaluation of the Biot-Savart integral in electrostatic problems with non-uniform Dirichlet boundary conditions [PDF]

, 2019
Robert Salazar, Camilo Bayona-Roa, J. S. Solís Chaves   +2 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Exact extraction of stress intensity factors via enriched numerical manifold method with composite patches. [PDF]

Sci Rep
Yang L, Bi Y, Wu M.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A time-domain Runge-Kutta dual reciprocity boundary element method for scalar wave propagation problem. [PDF]

Sci Rep
Zhou F, Deng J, Man J, Qin Y, Yu J, Zhang Y, Li W.   +6 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Unsteady two dimensional flow of non-newtönian fractional Casson fluid for an edge with heated boundaries. [PDF]

Sci Rep
Nadeem S, Hafeez K, Alzabut J, Zidan AM, Zigta B.   +4 more
europepmc   +1 more source