Results 101 to 110 of about 13,785 (292)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Pseudo-differential operators, heat calculus and index theory of groupoids satisfying the Lauter-Nistor condition [PDF]
In this thesis, we study singular pseudo-differential operators defined by groupoids satisfying the Lauter-Nistor condition, by a method parallel to that of manifolds with boundary and edge differential operators.
So, Bing Kwan
core
Calculus in Non-Integer-Dimensional Space: Tool for Fractal Physics
Fractal and FractionalIntegration in non-integer-dimensional spaces (NIDS) is actively used in quantum field theory, statistical physics, and fractal media physics. The integration over the entire momentum space with non-integer dimensions was first proposed by Wilson in 1973
Vasily E. Tarasov
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
On Higher Derivatives of Expectations [PDF]
It is understood that derivatives of an expectation $E [\phi(S(T)) | S(0) = x]$ with respect to $x$ can be expressed as $E [\phi(S(T)) \pi | S(0) = x]$, where $S(T)$ is a stochastic variable at time $T$ and $\pi$ is a stochastic weighting function ...
Robert de Rozario
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MathematicsQuantum calculus is a powerful extension of classical calculus, providing novel tools for deriving sharper and more efficient analytical results without relying on limits.
Amjad E. Hazma +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2012 This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Taylor & Francis.In this paper, a numerical implementation of a direct united boundary-domain integral equation (BDIE ...
Mikhailov, SE, Mohamed, NA
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An Asymptotic Expansion with Malliavin Weights: An Application to Pricing Discrete Barrier Options [PDF]
This paper proposes a new approximation method for pricing barrier options with discrete monitoring under stochastic volatility environment. In particular, the integration-by-parts formula in Malliavin calculus is effectively applied in an asymptotic ...
Akihiko Takahashi, Toshihiro Yamada
core +2 more sources