Results 161 to 170 of about 142,767 (307)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

A direct interaction of JAM-C with the tight junction scaffold protein ZO-2. [PDF]

open access: yesSci Rep
Schulte A   +7 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Comparative Analysis of Psychosocial Risks and Leadership in Municipal Government Agencies: A Study Based on NOM-035-STPS-2018 in Zacatecas, Mexico. [PDF]

open access: yesInt J Environ Res Public Health
Villagrán Rueda S   +7 more
europepmc   +1 more source

Full Elasticity in Atomic Monoids and Integral Domains [PDF]

open access: bronze, 2006
Scott T. Chapman   +2 more
openalex   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Comparative analysis of quality of life post coronary angioplasty and bypass surgery: A follow-up study on cardiac patients. [PDF]

open access: yesMedicine (Baltimore)
Shaphe MA   +7 more
europepmc   +1 more source

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