Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar +7 more
wiley +1 more source
Linking Individual Performance to Density-Dependent Population Dynamics to Understand Temperature-Mediated Genotype Coexistence. [PDF]
Bruijning M +9 more
europepmc +1 more source
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler +7 more
wiley +1 more source
Balancing Harvesting and Conservation: Demographic Responses of a Threatened Palm to Anthropogenic Disturbance. [PDF]
Mendes ETB, Portela RCQ.
europepmc +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
How Pastoral Are Pastoral Landscapes? Scavenger Assemblage Structure in Human-Dominated Landscapes: A Case Study From Mediterranean Pastures. [PDF]
Shapira O +3 more
europepmc +1 more source
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong +12 more
wiley +1 more source
Mucofilm: a nexus for phage-microbiome interactions in gut ecology. [PDF]
Mortensen AS +3 more
europepmc +1 more source
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li +9 more
wiley +1 more source
Phylogeographic and Ecological Insights Into the Evolutionary History of the Grass- and Sedge-Specializing Deltocephalinae Leafhoppers. [PDF]
Tian L +6 more
europepmc +1 more source

