Results 91 to 100 of about 263,102 (263)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Integrating Completely Unisolvent Functions
Journal of Approximation Theory, 1995 \(f:\mathbb{R}^n\times I\to\mathbb{R}\) is a continuous function and \(\text{INT}(f)\) is the set of all functions \(x\mapsto f(a_1, \dots, a_n,x)\) from \(\mathbb{R}\) to \(\mathbb{R}\). A function \(g\in \text{INT} (f)\) interpolates \(m\) points \((x_i,y_i)\in I\times R\), \(i=1,2, \dots,m\) if \(g(x_i)=y_i\) for all \(i\). The function \(f\) is \(n\
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Does a Functional Integral Really Need a Lagrangian?
Acta Polytechnica, 2010 Path integral formulation of quantum mechanics (and also other equivalent formulations) depends on a Lagrangian and/or Hamiltonian function that is chosen to describe the underlying classical system.
D. Kochan
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Electronic Journal of Differential Equations, 2006 We give an existence theorem for some functional-integral equations which includes many key integral and functional equations that arise in nonlinear analysis and its applications.
Josefa Caballero +2 more
doaj
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Solvability of m-product mixed non-linear functional integral equations
Beni-Suef University Journal of Basic and Applied SciencesThe purpose of this paper is devoted to establishing the existence of solutions for m-product non-linear functional integral equations with weakly singular and Riemann–Liouville integral terms.
Amar Deep +3 more
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On the approximation to integrable functions by integral functions [PDF]
Transactions of the American Mathematical Society, 1943 openaire +2 more sources