Results 51 to 60 of about 263,102 (263)
Abstract and Applied Analysis, 2015 We present a counterexample to the main result of the abovementioned paper showing that this result is false and cannot be improved in a simple way.
Krzysztof A. Topolski
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
On Mixed Quermassintegral for Log-Concave Functions
Journal of Function Spaces, 2020 In this paper, the functional Quermassintegral of log-concave functions in ℝn is discussed. We obtain the integral expression of the ith functional mixed Quermassintegral, which is similar to the integral expression of the ith mixed Quermassintegral of ...
Fangwei Chen +3 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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A Liapunov functional for a linear integral equation
Electronic Journal of Qualitative Theory of Differential Equations, 2010 In this note we consider a scalar integral equation $x(t)= a(t)-\int^t_0 C(t,s)x(s)ds$, together with its resolvent equation, $R(t,s)= C(t,s)-\int^t_s C(t,u) R(u,s)du$, where $C$ is convex. Using a Liapunov functional we show that for fixed $s$ then $|R(
Theodore Burton
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Functional integration over geometries [PDF]
Journal of Mathematical Physics, 1995 The geometric construction of the functional integral over coset spaces ℳ/𝒢 is reviewed. The inner product on the cotangent space of infinitesimal deformations of ℳ defines an invariant distance and volume form, or functional integration measure on the full configuration space.
openaire +3 more sources