Results 41 to 50 of about 3,163 (263)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On the probabilistic solution of the Cauchy problem for parabolic equations
Вестник КазНУ. Серия математика, механика, информатика, 2017 The questions about finding (conditional) mathematical expectations, the joint and marginal distribution of different functionals from the trajectories of random processes, expressed through the process itself, the ordinary stochastic integral and the ...
N. Akanbay, Z. Suleimenova
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
On a Method of Introducing Free-Infinitely Divisible Probability Measures
Demonstratio Mathematica, 2016 Random integral mappings give isomorphism between the subsemigroups of the classical (I D, *) and the free-infinite divisible (I D, ⊞) probability measures.
Jurek Zbigniew J.
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Disentangling long and short distances in momentum-space TMDs
Journal of High Energy Physics, 2022 The extraction of nonperturbative TMD physics is made challenging by prescriptions that shield the Landau pole, which entangle long- and short-distance contributions in momentum space.
Markus A. Ebert +3 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Measurable multifunctions and their applications to convex integral functionals
International Journal of Mathematics and Mathematical Sciences, 1989 The purpose of this paper is to establish some new properties of set valued measurable functions and of their sets of Integrable selectors and to use them to study convex integral functionals defined on Lebesgue-Bochner spaces.
Nikolaos S. Papageorgiou
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Weak approximation rates for integral functionals of Markov processes
Modern Stochastics: Theory and Applications, 2015 We obtain weak rates for approximation of an integral functional of a Markov process by integral sums. An assumption on the process is formulated only in terms of its transition probability density, and, therefore, our approach is not strongly dependent ...
Iurii Ganychenko, Alexei Kulik
doaj +1 more source