Results 91 to 100 of about 10,399,233 (265)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Units in Integral Group Rings - A Survey
, 2014 This is a short survey on units in integral group rings.
Juriaans, Stanley O.
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hochschild cohomology ring of the integral group ring of dihedral groups
Tsukuba Journal of Mathematics, 2007 We will determine the ring structure of the Hochschild cohomology $HH^{\ast}(\mathbb{Z}D_{2n})$ of the integral group ring of the dihedral group $D_{2n}$ of order $2n$.
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
On Torsion Units in Integral Group Ring of A Dicyclic Group
Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 2020 In this paper, the main aim is to characterize the structure of torsion units in integral group ring of dicyclic group by using a complex faithful irreducible representation of degree 2. We show by the first of Zassenhaus conjectures (ZC1) that non-trivial torsion units in are of order 3, 4 or 6 and each of them can be expressed in terms of 3 free ...
openaire +4 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On Hochschild cohomology ring of the integral group ring of the quaternion group
Tsukuba Journal of Mathematics, 2005 We will determine the ring structure of the Hochschild cohomology $HH^{*}(ZQ_{2})$ for the quatemion group $Q_{2}$ of order 8 using the ring isomorphism determined by Siegel and Witherspoon.
openaire +2 more sources