Results 121 to 130 of about 552,366 (332)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The radial heat equation and Laplace transforms [PDF]

open access: yes
Integral representations involving Laplace transforms developed for use in solutions of radial heat ...
Bragg, L. R.
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

ИССЛЕДОВАНИЕ МЕТОДА S-АППРОКСИМАЦИИ ДЛЯ РАЗЛИЧНЫХ ТИПОВ РЕЛЬЕФА ЗЕМНОЙ ПОВЕРХНОСТИ

open access: yesГеология и геофизика Юга России, 2018
В статье рассмотрены результаты исследований возможностей метода S-аппроксимации при построении аналитических аппроксимаций рельефа земной поверхности. Получены аналитические аппроксимации для различных типов рельефов местности (равнины, холмы и горы) и ...
И. А. Керимов   +3 more
doaj  

Extremal integral representations

open access: yesJournal of Functional Analysis, 1976
AbstractLet X be a closed bounded convex subset with the Radon-Nikodym property of a Banach space. For tight Borel probability measures μ, v on X, define μ ≺ v iff there is a dilation T on X such that T(μ) = v. Then, for every x ϵ X, there is a measure μ on X which is maximal in the partial order ≺ and which has barycenter x.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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