Results 141 to 150 of about 423 (186)

Cardiovascular β‐Adrenergic Receptor Distribution and Function: Influence of Species, Sex, Age, and Tissue

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid   +5 more
wiley   +1 more source

Extracellular Vesicles as Drivers of Lung Endothelial Dysfunction in ARDS: Mechanisms and Therapeutic Opportunities

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how extracellular vesicles from diverse pulmonary and extrapulmonary sources contribute to endothelial dysfunction in ARDS and evaluates emerging endothelial‐targeted therapies for their potential to mitigate EV‐mediated pathogenic mechanisms.
Mohammed Yaman Al Matni   +3 more
wiley   +1 more source

A Pseudo‐Two‐Dimensional Reaction–Diffusion Model for Rational Design of Antibacterial–Antioxidant Ag–ZnO/Fucoidan Nanocomposites

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
A pseudo‐two‐dimensional (P2D) reaction–diffusion framework is proposed to model reactive oxygen species (ROS) generation, transport, and scavenging in Ag–ZnO/Fucoidan nanocomposites. Spatially segregated ROS source (Ag–ZnO) and sink (fucoidan) domains are embedded into a one‐dimensional computational model, capturing nonlinear feedback between site ...
Mohamed Abu Shuheil   +8 more
wiley   +1 more source

A Multiphysics Engineering Model of pH and Oxygen Transport Limitations in Textile‐Based Wearable Lactate Biosensors

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
A one‐dimensional multiphysics engineering model is developed to elucidate the coupled transport and reaction phenomena governing textile‐based wearable lactate biosensors operating in sweat. The model integrates diffusion of lactate, oxygen, hydrogen peroxide, and protons with dual‐substrate enzymatic kinetics, acid–base equilibria, and mediator‐based
Kamel A. Saleh   +8 more
wiley   +1 more source

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