Results 121 to 130 of about 4,021,217 (356)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

A Semi-Analytical Solution of Two-Dimensional Unsteady Groundwater Flow Outside a Long-Strip Excavation Pit with a Cut-Off Wall

Applied Sciences
In deep excavation engineering, the implementation of cut-off walls stands as a crucial measure to ensure structural support stability. However, the existing theories for dewatering design often overlook the variations in cut-off wall penetration depths,
Yinsheng Chang, Le Lv, Xudong Wang, Jin Xu   +3 more
doaj   +1 more source

Integral Transforms in Relativistic Quantum Constraint Mechanics [PDF]

, 2011
R. Ducharme
openalex   +1 more source

Application of Integral Transforms Composition Method (ITCM) to obtaining transmutations via integral transforms with Bessel functions in kernels

, 2021
Elina Shishkina, С. М. Ситник, Inèss Jebabli   +2 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Mapping variations of redshift distributions with probability integral transforms [PDF]

, 2022
J. Myles, D. Gruen, A. Amon, A. Alarcon, Joseph DeRose, S. Everett, Scott Dodelson, G. M. Bernstein, A. Campos, I. Harrison, N. MacCrann, J. McCullough, Marco Raveri, C. Sánchez, M. A. Troxel, B. Yin, T. M. C. Abbott, S. Allam, O. Alves, F. Andrade-Oliveira, E. Bertin, D. Brooks, D. L. Burke, A. Carnero Rosell, M. Carrasco Kind, J. Carretero, R. Cawthon, M. Costanzi, L. da Costa, M. E. S. Pereira, S. Desai, P. Doel, I. Ferrero, B. Flaugher, J. Frieman, J. García-Bellido, M. Gatti, D. W. Gerdes, R. A. Gruendl, J. Gschwend, G. Gutiérrez, W G Hartley, S. R. Hinton, J. García-Bellido, K. Honscheid, D. J. James, K. Kuehn, O. Lahav, P. Melchior, J. Mena-Fernández, F. Menanteau, R. Miquel, J. J. Mohr, A. Palmese, F. Paz-Chinchón, A. Pieres, A. A. Plazas, J. Prat, M. Rodríguez-Monroy, E. Sánchez, V. Scarpine, I. Sevilla-Noarbe, M. Smith, E. Suchyta, M. E. C. Swanson, G. Tarlé, D. L. Tucker, M. Vincenzi, N. Weaverdyck   +68 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Analytical solution to linearized groundwater responses in sloping unconfined leaky aquifers under transient surface recharge

AIMS Mathematics
The increasing frequency of extreme climate events due to global warming has intensified water scarcity during prolonged droughts, highlighting the urgent need for effective water resource management.
Siao-Ya Tang, Ping-Cheng Hsieh
doaj   +1 more source

Partial Derivative Approach to the Integral Transform for the Function Space in the Banach Algebra. [PDF]

Entropy (Basel), 2020
Young Sik K.
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source