Results 71 to 80 of about 4,021,217 (356)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Dualities and applications of the new integral transform

AIP Advances
This paper presents the Abdallah group transform, a new integral transform for solving differential, partial, and integral equations, which is a generalization of the Jafari and polynomial integral transforms.
Borhen Halouani, Praveen Ailawalia, A. M. Abdallah   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

EXTENSION OF SOME INTEGRAL TRANSFORM BY THE METHOD OF MULTIPLE INTEGRALS [PDF]

Journal of Mechanics of Continua and Mathematical Sciences
Extension of some Integral Transform by the Method of Multiple Integrals by Lebesgue measurable and Lebesgue integrable.
https://jmcms.s3.amazonaws.com/wp-content/uploads/2024/08/24063139/jmcms-2408029-Extension-of-some-Integral-Transform-DG-DS-YJ-1.pdf, D. S. Singh, Yashawant Jaiswal3   +2 more
doaj   +1 more source

Some Parseval-Goldstein Type Theorems For Generalized Integral Transforms [PDF]

, 2023
Durmuş Albayrak
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Unification of integral transforms and their applications

Partial Differential Equations in Applied Mathematics
An integral transform called BA-transform is introduced in this work, which yields a known number of transforms by changing variables. We prove that Laplace, Sumudu, Natural, Elzaki, Aboodh, Tarig, Srivastava, Kamal, Laplace–Carson, Mohand, Shehu and ...
A. Belafhal, R. El Aitouni, T. Usman
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Single domain integral transform analysis of natural convection in cavities partially filled with heat generating porous medium

Numerical Heat Transfer, Part A Applications, 2018
An analysis of natural convection within a rectangular cavity partially filled with a heat-generating porous medium is carried out through the Generalized Integral Transform Technique (GITT), in which the laminar flow and energy equations are solved with
K. Lisboa, Jian Su, Renato Machado Cotta
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source