Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Integrating Occupational Health and Safety and Health Promotion: A Qualitative Study in Australia. [PDF]
Lu Y, Karanikas N, Carroll JA.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
From fragmentation to empowerment: community rehabilitation care and health literacy as drivers of integrated care. [PDF]
Maia AC, Félix A.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Integrated Management Strategies for Diabetes Mellitus and Hypertension: A Systematic Review. [PDF]
Nampalliwar A +5 more
europepmc +1 more source
Replication Data for: Integrated Traffic Flow Control in a Connected Network
Pétros Ioannou
openalex +1 more source
Guidelines Towards an Integrated Ocean Observation System for Ecosystems and Biogeochemical Cycles [PDF]
Hervé Claustre +22 more
openalex +1 more source
IMPLEMENTATION OF KURIKULUM MERDEKA IN INTEGRATED ISLAMIC SCHOOL
Yuli Marlina +2 more
openalex +2 more sources

