Results 231 to 240 of about 2,770,732 (298)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

ENabling VISions And Growing Expectations (ENVISAGE): Co-development and feasibility of an "integrated" version of ENVISAGE for service providers and parents of children with neurodevelopmental disabilities. [PDF]

Pilot Feasibility Stud
Soper AK, Wright M, Chambers E, Hughes D, Knutson M, Hesketh K, Hanson J, Rodrigues M, Cross A, Imms C, Babic R, O'Connor B, Phoenix M, Moll S, Rosenbaum P.   +14 more
europepmc   +1 more source

Coherence-Gradient Theory: A Unified Framework for Measuring Integrated Stability Across Complex Systems

Emma Dobbin
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Challenges in respiratory medicine: the need for integrated tuberculosis and respiratory care in low-resource settings. [PDF]

Thorax
Kagima JW, Ozoh OB, Mpagama S, Engel N, Lesosky M, Madan J, Chakaya J, Meghji J.   +7 more
europepmc   +1 more source

The GAB/BAG Integrated Model: A Governance Framework for AI and Blockchain in Swiss Private Banking

Hervé Racordon
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Integrating Multiparametric MRI and PSMA PET Imaging in Prostate Cancer: Toward a Unified Diagnostic and Risk-Stratification Paradigm. [PDF]

Medicina (Kaunas)
Pugliesi RA, Cannella R, Ben Mansour K, Di Biagio D, Alongi P.   +4 more
europepmc   +1 more source

Integrated Lithological and Depositional Facies Map of the Chennai Coastal Plain

Zarin Ali
openalex   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source