Results 71 to 80 of about 7,527,455 (262)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Integrated Assessment and Sustainable Water and Wetland Management. A Review of Concepts and Methods [PDF]

, 2005
This paper reviews and examines the potential of systematic and formalised interdisciplinary research concepts and methods for sustainable water and wetland policy and management, as advocated by the recently adopted EuropeanWater Framework Directive ...
Brouwer, R., Turner, R.K., Georgiou, S.
core  

Environmental and Health Impat Assessment of waste treatment: an integrated method applied at the case study of Padua Incinerator

, 2022
An integrated assessment which provide the health effect of an environmental exposure, due to stressor created during the incineration processreservedEmbargo permanente per motivi di segretezza e/o di proprietà dei risultati e informazioni di enti ...
Cardinale, Giovanna
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hazard analysis of typhoon-related external events using extreme value theory

Nuclear Engineering and Technology, 2015
Background: After the Fukushima accident, the importance of hazard analysis for extreme external events was raised. Methods: To analyze typhoon-induced hazards, which are one of the significant disasters of East Asian countries, a statistical analysis ...
Yochan Kim, Seung-Cheol Jang, Tae-Jin Lim   +2 more
doaj   +1 more source

Transparency and control in engineering integrated assessment models [PDF]

, 2005
Better software engineering such as archiving releases with version control, writing portable code, publishing documentation and results closely tied to the code improves integrated assessment models’ transparency and control.
Ha-Duong, Minh
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Integrated Assessment Model of Economy-Energy-Climate – The Model Wiagem [PDF]

, 2005
This paper presents an integrated economy-energy-climate model WIAGEM (World Integrated Assessment General Equilibrium Model) incorporating economic, energy and climatic modules in an integrated assessment approach. To evaluate market and nonmarket costs
Kemfert, Claudia
core  

The concepts and development of a participatory regional integrated assessment tool. [PDF]

, 2008
This paper provides an overview of the development of the ‘Regional Impact Simulator’ – a user friendly software tool designed to allow stakeholders to perform integrated assessments of the effects of climate and/or socio-economic change on the ...
Cojacaru, G., Holman, Ian P., Rounsevell, M.D.A., Rounsevell, M. D. A., Nicholls, R. J., Pearn, K. R., Berry, P. M., Holman, I.P., Nicholls, R.J., Rounsevell, Mark, Pearn, Kerry R., Henriques, C., Harrison, P.A., Mokrech, M., Audsley, E., McLachlan, C., Holman, I. P., Fontaine, C., Richards, J.A., Harrison, P. A., Audsley, Eric, Richards, J. A., Pearn, K.R., Berry, P.M., Shackley, S., Shackley, Simon   +25 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source