Results 191 to 200 of about 801,972 (259)

Involving Citizens in Integrated Care. Lessons Learned Through Participatory Action Research in Three Communities in the Netherlands. [PDF]

Int J Integr Care
Rutten GM, van Wijk E, Sleijster S, Oostra DL, Roenhorst J, Kleinjan M, Laurant M.   +6 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Physiotherapy-led integrated care (PTICOPE) for bladder symptoms and functional independence: A secondary analysis of a randomized controlled trial. [PDF]

J Taibah Univ Med Sci
Noordin N, Wah YC, Justine M.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Co-Design of a New Integrated Care Model With People Affected by Huntington's Disease: A Mixed Methods Study. [PDF]

Health Expect
Pires SB, Kunkel D, Manera K, Goodwin N, Kipps C, Portillo MC.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute-Care Utilization and Cost Offsets Associated With Language-Concordant, Pharmacist-Integrated Care Management Among High-Need, High-Cost Adults. [PDF]

Health Serv Res
Sioni SR, Manson L, Arledge N, Yanez J, Al Mouslmani M.   +4 more
europepmc   +1 more source

Multi-center disease-specific management system: toward standardized and harmonized clinical pathways in integrated care networks. [PDF]

Front Public Health
Liu X, Zhang R, Zheng T, Liu R, Zhang S, Zhao H, Dong J, Chen S, Xu J, Shi R.   +9 more
europepmc   +1 more source

224 From local to system-wide impact: scaling vaccination success through sustainable team-based collaboration to improve uptake in elderly population

BMJ Open Quality
Wilson Tee, Teo Cheng Rong, Goh Chin Thong, Kee Ah Gek, Chen Shu Ying, Teo Shao Chu, William Yap   +6 more
doaj   +1 more source